Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:FBW1B_HUMAN
Description:F-box and WD repeat domain containing 11 [Source:HGNC Symbol;Acc:13607]
Location:chr5 q35.1
Node attribute:ubiquitination(source); PPI(source)

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S541TYTYIsR____PhosphoSitePlus
Y411IACLQyRDRLVWD40PhosphoSitePlus
T536RSPSRtYTYISPhosphoSitePlus
Y539SRTYTyISR__PhosphoSitePlus
Y537SPSRTyTYISRPhosphoSitePlus

Dephosphorylation site
FBW1B_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000265094R236CCOSMICOvarian Cancer21720365

Differential expressed protein
FBW1B_HUMAN is not differential expressed protein.

Hyperphosphorylation site
FBW1B_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
FBW1B_HUMANIKBA_HUMANubiquitinationNetPath
FBW1B_HUMANGLI1_HUMANotherKEGG

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04340Hedgehog signaling pathway
hsa05131Shigellosis
hsa04310Wnt signaling pathway
hsa04120Ubiquitin mediated proteolysis
hsa04710Circadian rhythm - mammal
hsa04114Oocyte meiosis

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0007049cell cycleIEAbiological_process
GO:0005813centrosomeIDAcellular_component
GO:0004842ubiquitin-protein ligase activityIEAmolecular_function
GO:0005737cytoplasmIEAcellular_component
GO:0005829cytosolISScellular_component
GO:0046983protein dimerization activityIEAmolecular_function
GO:0005634nucleusIEAcellular_component
GO:0031146SCF-dependent proteasomal ubiquitin-dependent protIDAbiological_process
GO:0042753positive regulation of circadian rhythmIEAbiological_process
GO:0045893positive regulation of transcription, DNA-dependenIEAbiological_process
GO:0004842ubiquitin-protein ligase activityNASmolecular_function
GO:0019005SCF ubiquitin ligase complexIEAcellular_component
GO:0005634nucleusISScellular_component
GO:0045893positive regulation of transcription, DNA-dependenISSbiological_process
GO:0031648protein destabilizationIMPbiological_process
GO:0045892negative regulation of transcription, DNA-dependenIMPbiological_process
GO:0006470protein dephosphorylationISSbiological_process
GO:0000151ubiquitin ligase complexNAScellular_component
GO:0016055Wnt receptor signaling pathwayIEAbiological_process
GO:0000209protein polyubiquitinationIDAbiological_process
GO:0045862positive regulation of proteolysisIMPbiological_process
GO:0042347negative regulation of NF-kappaB import into nucleIEAbiological_process
GO:0000209protein polyubiquitinationIEAbiological_process
GO:0031146SCF-dependent proteasomal ubiquitin-dependent protIEAbiological_process
GO:0006470protein dephosphorylationIEAbiological_process
GO:0042753positive regulation of circadian rhythmISSbiological_process
GO:0016567protein ubiquitinationNASbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0005829cytosolIEAcellular_component
GO:0043161proteasomal ubiquitin-dependent protein catabolic IDAbiological_process
GO:0005515protein bindingIEAmolecular_function
GO:0019005SCF ubiquitin ligase complexIDAcellular_component
GO:0048511rhythmic processIEAbiological_process


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