Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:FAAH1_HUMAN
Description:fatty acid amide hydrolase [Source:HGNC Symbol;Acc:3553]
Location:chr1 p33
Node attribute:gene

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
T99EAVLFtYVGKAAmidasePhosphoSitePlus
S440NMKSRsAGKLWAmidasePhosphoSitePlus
Y454HEIEVyRKTVIAmidasePhosphoSitePlus
S434LSAFLsNMKSRAmidasePhosphoSitePlus
Y329PLRVGyYETDNAmidasePhosphoSitePlus
S430LLPRLsAFLSNAmidasePhosphoSitePlus
S88VQKLHsRELAPPhosphoSitePlus
T99EAVLFtYVGKAHPRD
Y329PLRVGyYETDNHPRD; phosphoELM
Y335YETDNyTMPSPHPRD; phosphoELM
Y335YETDNyTMPSPAmidasePhosphoSitePlus

Dephosphorylation site
FAAH1_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000243167K267MTCGAOvarian Cancer21720365, 18772890
ENSP00000243167S247FCOSMICSkin Cancer21984974
ENSP00000243167K267MCOSMICOvarian Cancer21720365
ENSP00000243167N259STCGAOvarian Cancer21720365, 18772890
ENSP00000243167N259SCOSMICOvarian Cancer21720365
ENSP00000243167A345DSjoblom2006, COSMIC, HPIBreast Cancer16959974
ENSP00000243167V543LBIOMARTBreast Cancer21930507, 21930502

Differential expressed protein
Ensembl IDCancer nameDesignSampleChangeRatioPubmed
ENSP00000243167Testicular CancerNormal vs. Cancercell lineDown18489135

Hyperphosphorylation site
FAAH1_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
IKZF1_HUMANFAAH1_HUMANTF -> target geneTRANSFAC

Function Annotation
KEGG Pathway
FAAH1_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0031090organelle membraneISScellular_component
GO:0047372acylglycerol lipase activityIEAmolecular_function
GO:0005737cytoplasmIDAcellular_component
GO:0017064fatty acid amide hydrolase activityIDAmolecular_function
GO:0005856cytoskeletonIEAcellular_component
GO:0016811hydrolase activity, acting on carbon-nitrogen (butIEAmolecular_function
GO:0016884carbon-nitrogen ligase activity, with glutamine asIEAmolecular_function
GO:0016021integral to membraneIEAcellular_component
GO:0012505endomembrane systemIEAcellular_component
GO:0009062fatty acid catabolic processIDAbiological_process


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