Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:FA7_HUMAN
Description:coagulation factor VII (serum prothrombin conversion accelerator) [Source:HGNC Symbol;Acc:3544]
Location:chr13 q34
Node attribute:ligand; gene

Phosphorylation site
FA7_HUMAN do not have phosphorylation site.

Dephosphorylation site
FA7_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000364731Y417*COSMICOvarian Cancer21720365
ENSP00000364731A266VCOSMICHead and Neck Cancer21798893

Differential expressed protein
Ensembl IDCancer nameDesignSampleChangeRatioPubmed
ENSP00000364731Lung CancerNormal vs. CancertissueDown12943690
ENSP00000364731Lung CancerNormal vs. CancertissueDown15626334
ENSP00000364731Lung CancerNormal vs. CancertissueUp15626334

Hyperphosphorylation site
FA7_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
FA7_HUMANTF_HUMANligand -> receptorHPMR
HNF4A_HUMANFA7_HUMANTF -> target geneTRANSFAC

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04610Complement and coagulation cascades

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0007598blood coagulation, extrinsic pathwayTASbiological_process
GO:0050927positive regulation of positive chemotaxisIDAbiological_process
GO:0005796Golgi lumenTAScellular_component
GO:0010641positive regulation of platelet-derived growth facIDAbiological_process
GO:0014070response to organic cyclic compoundIEAbiological_process
GO:0005788endoplasmic reticulum lumenTAScellular_component
GO:0002690positive regulation of leukocyte chemotaxisIDAbiological_process
GO:0043066negative regulation of apoptotic processTASbiological_process
GO:0031100organ regenerationIEAbiological_process
GO:0007596blood coagulationIEAbiological_process
GO:0043627response to estrogen stimulusIEAbiological_process
GO:0017187peptidyl-glutamic acid carboxylationTASbiological_process
GO:0004252serine-type endopeptidase activityIEAmolecular_function
GO:0005886plasma membraneTAScellular_component
GO:0001948glycoprotein bindingIPImolecular_function
GO:0030335positive regulation of cell migrationTASbiological_process
GO:0006508proteolysisTASbiological_process
GO:0007623circadian rhythmIEAbiological_process
GO:0005509calcium ion bindingIEAmolecular_function
GO:0031982vesicleIEAcellular_component
GO:0030194positive regulation of blood coagulationIEAbiological_process
GO:0005515protein bindingIEAmolecular_function
GO:0032571response to vitamin KIEAbiological_process
GO:0044267cellular protein metabolic processTASbiological_process
GO:0060416response to growth hormone stimulusIEAbiological_process
GO:0031667response to nutrient levelsIEAbiological_process
GO:0008236serine-type peptidase activityIEAmolecular_function
GO:0043687post-translational protein modificationTASbiological_process
GO:0051897positive regulation of protein kinase B signaling IDAbiological_process
GO:0008236serine-type peptidase activityTASmolecular_function
GO:0007596blood coagulationTASbiological_process
GO:0004175endopeptidase activityIEAmolecular_function
GO:0005102receptor bindingIEAmolecular_function
GO:0009725response to hormone stimulusIEAbiological_process
GO:0005615extracellular spaceIEAcellular_component
GO:0005576extracellular regionTAScellular_component
GO:0003824catalytic activityIEAmolecular_function


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