Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:FA11_HUMAN
Description:coagulation factor XI [Source:HGNC Symbol;Acc:3529]
Location:chr4 q35.2
Node attribute:gene

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y115CNKDIyVDLDMHPRD
Y125MKGINyNSSVAHPRD
Y125MKGINyNSSVAPAN_1PhosphoSitePlus
S128INYNSsVAKSAHPRD
S394VGGTAsVRGEWTrypsinPhosphoSitePlus
T22SGECVtQLLKDPAN_1PhosphoSitePlus
Y115CNKDIyVDLDMPAN_1PhosphoSitePlus
S128INYNSsVAKSAPAN_1PhosphoSitePlus
S17LFTSVsGECVTPhosphoSitePlus
Y608ERPGVyTNVVETrypsinPhosphoSitePlus

Dephosphorylation site
FA11_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000384957S250FBIOMARTBreast Cancer21930507, 21930502

Differential expressed protein
FA11_HUMAN is not differential expressed protein.

Hyperphosphorylation site
FA11_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
HNF4A_HUMANFA11_HUMANTF -> target geneTRANSFAC

Function Annotation
KEGG Pathway
FA11_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0031639plasminogen activationIDAbiological_process
GO:0016020membraneNAScellular_component
GO:0008201heparin bindingIEAmolecular_function
GO:0007596blood coagulationIEAbiological_process
GO:0005615extracellular spaceIDAcellular_component
GO:0030193regulation of blood coagulationIEAbiological_process
GO:0051919positive regulation of fibrinolysisIDAbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0044421extracellular region partIEAcellular_component
GO:0006508proteolysisIEAbiological_process
GO:0003824catalytic activityIEAmolecular_function
GO:0070009serine-type aminopeptidase activityIEAmolecular_function
GO:0007597blood coagulation, intrinsic pathwayTASbiological_process
GO:0005886plasma membraneTAScellular_component
GO:0004252serine-type endopeptidase activityNASmolecular_function
GO:0005576extracellular regionNAScellular_component


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