| UniProt/SwissProt ID: | FA11_HUMAN |
| Description: | coagulation factor XI [Source:HGNC Symbol;Acc:3529] |
| Location: | chr4 q35.2 |
| Node attribute: | gene |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| Y115 | CNKDIyVDLDM | HPRD | |
| Y125 | MKGINyNSSVA | HPRD | |
| Y125 | MKGINyNSSVA | PAN_1 | PhosphoSitePlus |
| S128 | INYNSsVAKSA | HPRD | |
| S394 | VGGTAsVRGEW | Trypsin | PhosphoSitePlus |
| T22 | SGECVtQLLKD | PAN_1 | PhosphoSitePlus |
| Y115 | CNKDIyVDLDM | PAN_1 | PhosphoSitePlus |
| S128 | INYNSsVAKSA | PAN_1 | PhosphoSitePlus |
| S17 | LFTSVsGECVT | PhosphoSitePlus | |
| Y608 | ERPGVyTNVVE | Trypsin | PhosphoSitePlus |
| Dephosphorylation site |
| FA11_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000384957 | S250F | BIOMART | Breast Cancer | 21930507, 21930502 |
| Differential expressed protein |
| FA11_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| FA11_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| HNF4A_HUMAN | FA11_HUMAN | TF -> target gene | TRANSFAC |
| Function Annotation |
| KEGG Pathway |
| FA11_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0031639 | plasminogen activation | IDA | biological_process |
| GO:0016020 | membrane | NAS | cellular_component |
| GO:0008201 | heparin binding | IEA | molecular_function |
| GO:0007596 | blood coagulation | IEA | biological_process |
| GO:0005615 | extracellular space | IDA | cellular_component |
| GO:0030193 | regulation of blood coagulation | IEA | biological_process |
| GO:0051919 | positive regulation of fibrinolysis | IDA | biological_process |
| GO:0005515 | protein binding | IPI | molecular_function |
| GO:0044421 | extracellular region part | IEA | cellular_component |
| GO:0006508 | proteolysis | IEA | biological_process |
| GO:0003824 | catalytic activity | IEA | molecular_function |
| GO:0070009 | serine-type aminopeptidase activity | IEA | molecular_function |
| GO:0007597 | blood coagulation, intrinsic pathway | TAS | biological_process |
| GO:0005886 | plasma membrane | TAS | cellular_component |
| GO:0004252 | serine-type endopeptidase activity | NAS | molecular_function |
| GO:0005576 | extracellular region | NAS | cellular_component |