Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:EPCR_HUMAN
Description:protein C receptor, endothelial [Source:HGNC Symbol;Acc:9452]
Location:chr20 q11.22
Node attribute:receptor

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
T204TKGSQtSRSYTPhosphoSitePlus
S195VQKHIsAENTKPhosphoSitePlus

Dephosphorylation site
EPCR_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000216968Q83*COSMICHead and Neck Cancer21798893

Differential expressed protein
Ensembl IDCancer nameDesignSampleChangeRatioPubmed
ENSP00000216968Breast CancerTreatment (tamoxifen-sensitive vs. tamoxifen-resistant)tissueDown0.5219329653

Hyperphosphorylation site
EPCR_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
PROC_HUMANEPCR_HUMANligand -> receptorHPMR

Function Annotation
KEGG Pathway
EPCR_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005515protein bindingIPImolecular_function
GO:0005887integral to plasma membraneTAScellular_component
GO:0019882antigen processing and presentationIEAbiological_process
GO:0006955immune responseIEAbiological_process
GO:0050819negative regulation of coagulationIMPbiological_process
GO:0005813centrosomeIEAcellular_component
GO:0042612MHC class I protein complexIEAcellular_component
GO:0004872receptor activityTASmolecular_function
GO:0016020membraneIEAcellular_component
GO:0007596blood coagulationIEAbiological_process


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