Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:ENAH_HUMAN
Description:enabled homolog (Drosophila) [Source:HGNC Symbol;Acc:18271]
Location:chr1 q42.12
Node attribute:PPI(target)

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S528VFDNRsYDSLHPhosphoSitePlus
S265RERRIsSAAAPPhosphoSitePlus
S486TSKASsTSTPEPhosphoSitePlus
T487SKASStSTPEPPhosphoSitePlus
T116LNSQEtGPTLPPhosphoSitePlus
S405KLRKVsRMEDTPhosphoSitePlus; HPRD; phosphoELM; SysPTM
T481DSEPVtSKASSPhosphoSitePlus
T517SRPKStPLSQPHPRD
S506NTMNGsKSPVIPhosphoSitePlus; HPRD; phosphoELM
S512KSPVIsRRDSPPhosphoSitePlus
T500KPWERtNTMNGPhosphoSitePlus
S520KSTPLsQPSANHPRD
S516ISRRDsPRKNQPhosphoSitePlus
T502WERTNtMNGSKPhosphoSitePlus; HPRD; phosphoELM; SysPTM
S541KSTPLsQPSANHPRD; phosphoELM
S266ERRISsAAAPAPhosphoSitePlus
T410SRMEDtSFPSGPhosphoSitePlus; HPRD; phosphoELM; SysPTM
S508MNGSKsPVISRPhosphoSitePlus; HPRD; phosphoELM
T119QETGPtLPRQNPhosphoSitePlus
Y529FDNRSyDSLHRPhosphoSitePlus
T538HRPKStPLSQPHPRD; phosphoELM
T489ASSTStPEPTRPhosphoSitePlus; HPRD; phosphoELM; SysPTM
Y16AAVMVyDDANKWH1PhosphoSitePlus
S485VTSKAsSTSTPPhosphoSitePlus
S125LPRQNsQLPAQPhosphoSitePlus; HPRD; phosphoELM; SysPTM

Dephosphorylation site
ENAH_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000355808Q130*BIOMARTBreast Cancer21930507, 21930502
ENSP00000355809R240WCOSMICMelanoma21499247
ENSP00000355808Q151KBIOMARTBreast Cancer21930507, 21930502
ENSP00000355809Q151KBIOMARTBreast Cancer21930507, 21930502
ENSP00000355809S531TCOSMICHead and Neck Cancer21798893
ENSP00000355809Q130*BIOMARTBreast Cancer21930507, 21930502

Differential expressed protein
Ensembl IDCancer nameDesignSampleChangeRatioPubmed
ENSP00000355809Ovarian CancerMetastasiscell lineUp17892554

Hyperphosphorylation site
ENAH_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
BAIP2_HUMANENAH_HUMANotherKEGG

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04810Regulation of actin cytoskeleton

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0050852T cell receptor signaling pathwayTASbiological_process
GO:0030036actin cytoskeleton organizationIEAbiological_process
GO:0030054cell junctionIDAcellular_component
GO:0005515protein bindingIEAmolecular_function
GO:0030175filopodiumIEAcellular_component
GO:0001843neural tube closureIEAbiological_process
GO:0005829cytosolTAScellular_component
GO:0005925focal adhesionIDAcellular_component
GO:0007411axon guidanceTASbiological_process
GO:0046907intracellular transportIEAbiological_process
GO:0050699WW domain bindingIPImolecular_function
GO:0045202synapseIEAcellular_component
GO:0030027lamellipodiumIEAcellular_component
GO:0005737cytoplasmIDAcellular_component
GO:0001725stress fiberIEAcellular_component
GO:0007411axon guidanceIEAbiological_process
GO:0005886plasma membraneIDAcellular_component
GO:0008154actin polymerization or depolymerizationIEAbiological_process
GO:0017124SH3 domain bindingIEAmolecular_function
GO:0003779actin bindingIEAmolecular_function


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