| UniProt/SwissProt ID: | ELL3_HUMAN |
| Description: | elongation factor RNA polymerase II-like 3 [Source:HGNC Symbol;Acc:23113] |
| Location: | chr15 q15.3 |
| Node attribute: | substrate |
| Phosphorylation site |
| ELL3_HUMAN do not have phosphorylation site. |
| Dephosphorylation site |
| ELL3_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000320346 | G385S | COSMIC | Skin Cancer | 21984974 | ENSP00000320346 | R320C | COSMIC | Ovarian Cancer | 21720365 |
| Differential expressed protein |
| ELL3_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| ELL3_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| ST17A_HUMAN | ELL3_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| Function Annotation |
| KEGG Pathway |
| ELL3_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0032786 | positive regulation of DNA-dependent transcription | IDA | biological_process |
| GO:0048863 | stem cell differentiation | ISS | biological_process |
| GO:0010717 | regulation of epithelial to mesenchymal transition | ISS | biological_process |
| GO:0006368 | transcription elongation from RNA polymerase II pr | IDA | biological_process |
| GO:0006354 | DNA-dependent transcription, elongation | IDA | biological_process |
| GO:0035326 | enhancer binding | ISS | molecular_function |
| GO:0005634 | nucleus | IDA | cellular_component |
| GO:0006366 | transcription from RNA polymerase II promoter | ISS | biological_process |
| GO:0008023 | transcription elongation factor complex | NAS | cellular_component |
| GO:0045944 | positive regulation of transcription from RNA poly | IDA | biological_process |
| GO:0005730 | nucleolus | IDA | cellular_component |
| GO:0007283 | spermatogenesis | NAS | biological_process |