| UniProt/SwissProt ID: | ELF2_HUMAN |
| Description: | E74-like factor 2 (ets domain transcription factor) [Source:HGNC Symbol;Acc:3317] |
| Location: | chr4 q31.1 |
| Node attribute: | TF |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| T414 | TSTSPtTATSP | HPRD | |
| T367 | STSPTtATSPK | HPRD | |
| S412 | LITSTsPTTAT | HPRD | |
| S131 | PISNGsPELGI | HPRD | |
| S179 | PISNGsPELGI | HPRD | |
| S173 | PKTQQsPISNG | HPRD | |
| S128 | QQSPIsNGSPE | HPRD | |
| T417 | SPTTAtSPKVV | HPRD | |
| T366 | TSTSPtTATSP | HPRD | |
| S360 | DASSRsPTTTA | HPRD | |
| S351 | VVNITsPGHDA | HPRD | |
| S176 | QQSPIsNGSPE | HPRD | |
| T369 | SPTTAtSPKVV | HPRD | |
| S303 | VVNITsPGHDA | HPRD | |
| S125 | PKTQQsPISNG | HPRD | |
| S364 | LITSTsPTTAT | HPRD | |
| S418 | PTTATsPKVVI | HPRD | |
| S191 | PISNGsPELGI | phosphoELM; SysPTM | |
| T509 | QASGQtPPRVI | HPRD | |
| T314 | SSRSPtTTASV | HPRD | |
| S362 | APLITsTSPTT | HPRD | |
| S312 | DASSRsPTTTA | HPRD | |
| S410 | APLITsTSPTT | HPRD | |
| T362 | SSRSPtTTASV | HPRD | |
| T122 | GRKPKtQQSPI | HPRD | |
| S370 | PTTATsPKVVI | HPRD | |
| T461 | QASGQtPPRVI | HPRD | |
| T170 | GRKPKtQQSPI | HPRD | |
| T415 | STSPTtATSPK | HPRD | |
| Dephosphorylation site |
| ELF2_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000377782 | Y215F | COSMIC | Melanoma | 21499247 | ENSP00000265495 | Y215F | COSMIC | Melanoma | 21499247 |
| Differential expressed protein |
| ELF2_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| ELF2_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| ELF2_HUMAN | LYN_HUMAN | TF -> target gene | TRANSFAC |
| ELF2_HUMAN | UROK_HUMAN | TF -> target gene | TRANSFAC |
| Function Annotation |
| KEGG Pathway |
| ELF2_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0045892 | negative regulation of transcription, DNA-dependen | IDA | biological_process |
| GO:0045893 | positive regulation of transcription, DNA-dependen | IDA | biological_process |
| GO:0005515 | protein binding | IEA | molecular_function |
| GO:0003700 | sequence-specific DNA binding transcription factor | IEA | molecular_function |
| GO:0006355 | regulation of transcription, DNA-dependent | IEA | biological_process |
| GO:0006351 | transcription, DNA-dependent | IEA | biological_process |
| GO:0043565 | sequence-specific DNA binding | IEA | molecular_function |
| GO:0005737 | cytoplasm | IDA | cellular_component |
| GO:0006357 | regulation of transcription from RNA polymerase II | IDA | biological_process |
| GO:0005634 | nucleus | IDA | cellular_component |
| GO:0005515 | protein binding | IPI | molecular_function |