Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:EDN2_HUMAN
Description:endothelin 2 [Source:HGNC Symbol;Acc:3177]
Location:chr1 p34.2
Node attribute:ligand

Phosphorylation site
EDN2_HUMAN do not have phosphorylation site.

Dephosphorylation site
EDN2_HUMAN do not have dephosphorylation site.

Mutation site
EDN2_HUMAN do not have mutation site.

Differential expressed protein
EDN2_HUMAN is not differential expressed protein.

Hyperphosphorylation site
EDN2_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
EDN2_HUMANEDNRA_HUMANligand -> receptorHPMR

Function Annotation
KEGG Pathway
EDN2_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0048016inositol phosphate-mediated signalingIDAbiological_process
GO:0045987positive regulation of smooth muscle contractionIEAbiological_process
GO:0042116macrophage activationIDAbiological_process
GO:0001516prostaglandin biosynthetic processIEAbiological_process
GO:0008284positive regulation of cell proliferationIDAbiological_process
GO:0005576extracellular regionTAScellular_component
GO:0014824artery smooth muscle contractionIDAbiological_process
GO:0019722calcium-mediated signalingIDAbiological_process
GO:0060585positive regulation of prostaglandin-endoperoxide IMPbiological_process
GO:0005179hormone activityIDAmolecular_function
GO:0007166cell surface receptor signaling pathwayICbiological_process
GO:0019221cytokine-mediated signaling pathwayIDAbiological_process
GO:0060585positive regulation of prostaglandin-endoperoxide IEAbiological_process
GO:0014826vein smooth muscle contractionIDAbiological_process
GO:0010460positive regulation of heart rateIDAbiological_process
GO:0048246macrophage chemotaxisIDAbiological_process
GO:0019229regulation of vasoconstrictionIEAbiological_process
GO:0003058hormonal regulation of the force of heart contractTASbiological_process
GO:0003100regulation of systemic arterial blood pressure by IDAbiological_process
GO:0002690positive regulation of leukocyte chemotaxisIDAbiological_process
GO:0001516prostaglandin biosynthetic processIDAbiological_process
GO:0003099positive regulation of the force of heart contractTASbiological_process
GO:0005615extracellular spaceIDAcellular_component
GO:0042310vasoconstrictionIDAbiological_process
GO:0030593neutrophil chemotaxisIDAbiological_process
GO:0007204elevation of cytosolic calcium ion concentrationIDAbiological_process


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