Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:E2F3_HUMAN
Description:E2F transcription factor 3 [Source:HGNC Symbol;Acc:3115]
Location:chr6 p22.3
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
T169PDSPKtPKSPSPhosphoSitePlus
S124LGRGGsGGGGGPhosphoSitePlus
S172PKTPKsPSEKTPhosphoSitePlus
Y349GPIEVyLCPEEPhosphoSitePlus
S166LRSPDsPKTPKPhosphoSitePlus
T152SDGLKtPKGKGPhosphoSitePlus
S174TPKSPsEKTRYPhosphoSitePlus
Y179SEKTRyDTSLGphosphoELM
S182TRYDTsLGLLTphosphoELM
S163RAALRsPDSPKPhosphoSitePlus

Dephosphorylation site
E2F3_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000262904G184CCOSMICLung Cancer

Differential expressed protein
E2F3_HUMAN is not differential expressed protein.

Hyperphosphorylation site
E2F3_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
ACVR1_HUMANE2F3_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
E2F3_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005515protein bindingIPImolecular_function
GO:0005667transcription factor complexIEAcellular_component
GO:0005515protein bindingIEAmolecular_function
GO:0006355regulation of transcription, DNA-dependentIEAbiological_process
GO:0005654nucleoplasmTAScellular_component
GO:0000085G2 phase of mitotic cell cycleTASbiological_process
GO:0003700sequence-specific DNA binding transcription factorIEAmolecular_function
GO:0000080G1 phase of mitotic cell cycleTASbiological_process
GO:0045893positive regulation of transcription, DNA-dependenIEAbiological_process
GO:0006367transcription initiation from RNA polymerase II prTASbiological_process
GO:0003677DNA bindingIEAmolecular_function
GO:0000278mitotic cell cycleTASbiological_process
GO:0001047core promoter bindingIDAmolecular_function
GO:0008284positive regulation of cell proliferationIEAbiological_process


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