| UniProt/SwissProt ID: | DUT_HUMAN |
| Description: | deoxyuridine triphosphatase [Source:HGNC Symbol;Acc:3078] |
| Location: | chr15 q21.1 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| T7 | AISP | HPRD | |
| T151 | QALDDtERGSG | HPRD | |
| T138 | GGFGStG | HPRD | |
| T239 | QALDDtERGSG | dUTPase | PhosphoSitePlus |
| S11 | ETPAIsPSKRA | CDK1 | HPRD |
| T128 | QALDDtERGSG | HPRD | |
| T161 | GGFGStG | HPRD | |
| T249 | GGFGStG | HPRD | |
| S21 | TSLLRsAMQNA | PhosphoSitePlus | |
| S88 | PKAGGsPAPGP | PhosphoSitePlus; HPRD | |
| Y167 | LPSGCyGRVAP | dUTPase | PhosphoSitePlus |
| S13 | PAISPsKRARP | HPRD | |
| S132 | DTERGsGGFGS | HPRD | |
| S155 | DTERGsGGFGS | HPRD | |
| T239 | QALDDtERGSG | HPRD; phosphoELM | |
| S243 | DTERGsGGFGS | HPRD | |
| S99 | ETPAIsPSKRA | CDC2 | RegPhos; SysPTM |
| S99 | ETPAIsPSKRA | PhosphoSitePlus; HPRD; phosphoELM; RegPhos; SysPTM | |
| S160 | SGGFGsTG | HPRD | |
| S248 | SGGFGsTG | HPRD; phosphoELM | |
| S137 | SGGFGsTG | HPRD | |
| Dephosphorylation site |
| DUT_HUMAN do not have dephosphorylation site. |
| Mutation site |
| DUT_HUMAN do not have mutation site. |
| Differential expressed protein |
| DUT_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| DUT_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| ZAGL2_HUMAN | DUT_HUMAN | kinase -> substrate | RegPhos |
| CDK1_HUMAN | DUT_HUMAN | kinase -> substrate | HPRD; RegPhos |
| ST17A_HUMAN | DUT_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa00240 | Pyrimidine metabolism |
| hsa01100 | Metabolic pathways |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0046080 | dUTP metabolic process | IEA | biological_process |
| GO:0004170 | dUTP diphosphatase activity | EXP | molecular_function |
| GO:0006260 | DNA replication | TAS | biological_process |
| GO:0055086 | nucleobase-containing small molecule metabolic pro | TAS | biological_process |
| GO:0005634 | nucleus | TAS | cellular_component |
| GO:0005739 | mitochondrion | IEA | cellular_component |
| GO:0046134 | pyrimidine nucleoside biosynthetic process | TAS | biological_process |
| GO:0005515 | protein binding | IPI | molecular_function |
| GO:0006139 | nucleobase-containing compound metabolic process | TAS | biological_process |
| GO:0006206 | pyrimidine nucleobase metabolic process | TAS | biological_process |
| GO:0006226 | dUMP biosynthetic process | IEA | biological_process |
| GO:0016787 | hydrolase activity | IEA | molecular_function |
| GO:0044281 | small molecule metabolic process | TAS | biological_process |
| GO:0005654 | nucleoplasm | TAS | cellular_component |