| UniProt/SwissProt ID: | DNJC5_HUMAN |
| Description: | DnaJ (Hsp40) homolog, subfamily C, member 5 [Source:HGNC Symbol;Acc:16235] |
| Location: | chr20 q13.33 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S10 | RQRSLsTSGES | PhosphoSitePlus; HPRD; phosphoELM; RegPhos; SysPTM | |
| S8 | DQRQRsLSTSG | PhosphoSitePlus; HPRD; phosphoELM; RegPhos | |
| Y17 | SGESLyHVLGL | HPRD; phosphoELM | |
| Y192 | DSHPSyHTDGF | PhosphoSitePlus | |
| S12 | RSLSTsGESLY | PhosphoSitePlus; HPRD; RegPhos | |
| T11 | QRSLStSGESL | PhosphoSitePlus; HPRD; phosphoELM; RegPhos; SysPTM | |
| Y149 | EETEFyVSPED | PhosphoSitePlus | |
| Y17 | SGESLyHVLGL | DnaJ | PhosphoSitePlus |
| S10 | RQRSLsTSGES | PRKACA | HPRD; SysPTM |
| S15 | STSGEsLYHVL | DnaJ | PhosphoSitePlus |
| S34 | DDIKKsYRKLA | DnaJ | PhosphoSitePlus |
| S15 | STSGEsLYHVL | HPRD; phosphoELM; RegPhos | |
| S10 | RQRSLsTSGES | PKACa | RegPhos; SysPTM |
| Y42 | KLALKyHPDKN | DnaJ | PhosphoSitePlus |
| Dephosphorylation site |
| DNJC5_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000354111 | D45N | COSMIC | Pancreatic Cancer | 21252315 |
| Differential expressed protein |
| Ensembl ID | Cancer name | Design | Sample | Change | Ratio | Pubmed |
|---|---|---|---|---|---|---|
| ENSP00000354111 | Testicular Cancer | Normal vs. Cancer | cell line | Up | 18489135 | |
| Hyperphosphorylation site |
| DNJC5_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| ZAGL2_HUMAN | DNJC5_HUMAN | kinase -> substrate | RegPhos |
| KPCA_HUMAN | DNJC5_HUMAN | kinase -> substrate | HPRD |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa04141 | Protein processing in endoplasmic reticulum |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0042470 | melanosome | IEA | cellular_component |
| GO:0001948 | glycoprotein binding | IEA | molecular_function |
| GO:0061202 | clathrin-sculpted gamma-aminobutyric acid transpor | TAS | cellular_component |
| GO:0007268 | synaptic transmission | TAS | biological_process |
| GO:0008219 | cell death | IEA | biological_process |
| GO:0043008 | ATP-dependent protein binding | IEA | molecular_function |
| GO:0007269 | neurotransmitter secretion | TAS | biological_process |
| GO:0008021 | synaptic vesicle | IEA | cellular_component |
| GO:0006457 | protein folding | IEA | biological_process |
| GO:0043524 | negative regulation of neuron apoptotic process | IEA | biological_process |
| GO:0005886 | plasma membrane | IDA | cellular_component |
| GO:0031072 | heat shock protein binding | IEA | molecular_function |
| GO:0051082 | unfolded protein binding | IEA | molecular_function |