| UniProt/SwissProt ID: | DLL3_HUMAN |
| Description: | delta-like 3 (Drosophila) [Source:HGNC Symbol;Acc:2909] |
| Location: | chr19 q13.2 |
| Node attribute: | PPI(source) |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| T126 | SFIIEtWREEL | PhosphoSitePlus | |
| T119 | DAWPGtFSFII | PhosphoSitePlus | |
| S521 | RRRGHsQDAGS | HPRD | |
| S526 | SQDAGsRLLAG | HPRD | |
| S121 | WPGTFsFIIET | PhosphoSitePlus | |
| Dephosphorylation site |
| DLL3_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000205143 | P111S | COSMIC | Central Nervous System Neoplasms | 18772890 | ENSP00000205143 | P104S | TCGA | Neoplasms by Histologic Type | 21720365, 18772890 | ENSP00000205143 | P111S | TCGA | Neoplasms by Histologic Type | 21720365, 18772890 | ENSP00000205143 | P104S | COSMIC | Central Nervous System Neoplasms | 18772890 |
| Differential expressed protein |
| DLL3_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| DLL3_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| DLL3_HUMAN | NOTC1_HUMAN | other | KEGG |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa04330 | Notch signaling pathway |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0007275 | multicellular organismal development | IEA | biological_process |
| GO:0001501 | skeletal system development | IEA | biological_process |
| GO:0007219 | Notch signaling pathway | IEA | biological_process |
| GO:0005112 | Notch binding | NAS | molecular_function |
| GO:0001501 | skeletal system development | IMP | biological_process |
| GO:0016021 | integral to membrane | NAS | cellular_component |
| GO:0005509 | calcium ion binding | IEA | molecular_function |
| GO:0009888 | tissue development | IEA | biological_process |
| GO:0005515 | protein binding | IEA | molecular_function |
| GO:0007386 | compartment pattern specification | IEA | biological_process |
| GO:0050768 | negative regulation of neurogenesis | IEA | biological_process |
| GO:0001756 | somitogenesis | IEA | biological_process |
| GO:0048339 | paraxial mesoderm development | IEA | biological_process |