Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:DLGP5_HUMAN
Description:discs, large (Drosophila) homolog-associated protein 5 [Source:HGNC Symbol;Acc:16864]
Location:chr14 q22.3
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S368KCKTYsTKTIQGKAPPhosphoSitePlus
S618FFRVEsPVKLFPhosphoSitePlus; HPRD; phosphoELM
S353TEVDEsQATKEGKAPPhosphoSitePlus
T338ANAFLtPSYTWGKAPPhosphoSitePlus
S806CHLLDsPGLNCPhosphoSitePlus; HPRD; phosphoELM
S634SSEGPsQRLGTPhosphoSitePlus; HPRD
S624PVKLFsGLSVSPhosphoSitePlus; HPRD; phosphoELM
S689IPESRsSIEDAPhosphoSitePlus; HPRD; phosphoELM
T326KTYQVtPMTPRGKAPPhosphoSitePlus
S28IAHRKsLSQKEPhosphoSitePlus
S30HRKSLsQKENRPhosphoSitePlus
T329QVTPMtPRSANHPRD; phosphoELM
S332PMTPRsANAFLGKAPPhosphoSitePlus
T401NKNEAtTKNLNGKAPPhosphoSitePlus
S67ELDETsQGLVPPhosphoSitePlus
T223RTVSStTARKPHPRD
S839NLITFsPLQPGPhosphoSitePlus; HPRD; phosphoELM
T469KDLIRtAVGQTGKAPPhosphoSitePlus
S662PQQTTsPENAGPhosphoSitePlus; HPRD; phosphoELM
T224TVSSTtARKPVHPRD; phosphoELM
T344PSYTWtPLKTEGKAPPhosphoSitePlus
S222PRTVSsTTARKHPRD
S188SEKKVsDKEKKPhosphoSitePlus
T326KTYQVtPMTPRHPRD; phosphoELM
T348WTPLKtEVDESGKAPPhosphoSitePlus
T784LEEGEtKISQSPhosphoSitePlus; HPRD; phosphoELM
T201QPVMPtSLRMTPhosphoSitePlus
S757MELNSsITSQDPhosphoSitePlus
S687LSIPEsRSSIEPhosphoSitePlus; HPRD; phosphoELM
T329QVTPMtPRSANGKAPPhosphoSitePlus
T759LNSSItSQDVLPhosphoSitePlus
S725SSERMsLPLLAPhosphoSitePlus; HPRD; phosphoELM
S812PGLNCsNPFTQPhosphoSitePlus; HPRD; phosphoELM
T338ANAFLtPSYTWHPRD; phosphoELM
S221VPRTVsSTTARPhosphoSitePlus; HPRD
T441ILQSEtEKLTSHPRD
S830HARHIsFGGNLPhosphoSitePlus; HPRD; phosphoELM
S630GLSVSsEGPSQPhosphoSitePlus; HPRD; phosphoELM
S8SSHFAsRHRKDPhosphoSitePlus
S787GETKIsQSELFPhosphoSitePlus; HPRD
S376TIQQDsNKLPCGKAPPhosphoSitePlus
S306IKGKNsFAPKDPhosphoSitePlus; HPRD
S629SGLSVsSEGPSHPRD
S720KVDCLsSERMSPhosphoSitePlus; HPRD; phosphoELM
T639SQRLGtPKSVNPhosphoSitePlus; HPRD; phosphoELM
S627LFSGLsVSSEGPhosphoSitePlus; HPRD
T219KQVPRtVSSTTPhosphoSitePlus; HPRD; phosphoELM
S789TKISQsELFDNPhosphoSitePlus; HPRD
T344PSYTWtPLKTEHPRD; phosphoELM
S777TASQNsILEEGPhosphoSitePlus; HPRD; phosphoELM
T402KNEATtKNLNGGKAPPhosphoSitePlus
T182PGPRQtSEKKVPhosphoSitePlus
T661IPQQTtSPENAHPRD
S690PESRSsIEDAQPhosphoSitePlus; HPRD; phosphoELM
T837GGNLItFSPLQPhosphoSitePlus
T799NKSLTtECHLLHPRD; phosphoELM
T356DESQAtKEILAGKAPPhosphoSitePlus
T342LTPSYtWTPLKGKAPPhosphoSitePlus
T441ILQSEtEKLTSGKAPPhosphoSitePlus
S202PVMPTsLRMTRPhosphoSitePlus
S774EKNTAsQNSILPhosphoSitePlus; HPRD
S642LGTPKsVNKAVPhosphoSitePlus; HPRD; phosphoELM
T84PRAMKtILGDQPhosphoSitePlus

Dephosphorylation site
DLGP5_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000247191D713HBIOMARTBreast Cancer21930507, 21930502
ENSP00000247191G178DCOSMICSkin Cancer21984974
ENSP00000247191E722DBIOMARTBreast Cancer21930507, 21930502
ENSP00000247191C381GCOSMICOvarian Cancer21720365
ENSP00000247191L466VCOSMICOvarian Cancer21720365
ENSP00000247191L203FCOSMICHead and Neck Cancer21798893

Differential expressed protein
DLGP5_HUMAN is not differential expressed protein.

Hyperphosphorylation site
DLGP5_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
CDK1_HUMANDLGP5_HUMANkinase -> substrateRegPhos
ZAGL2_HUMANDLGP5_HUMANkinase -> substrateRegPhos

Function Annotation
KEGG Pathway
DLGP5_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0008283cell proliferationNASbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0004721phosphoprotein phosphatase activityISSmolecular_function
GO:0031616spindle pole centrosomeISScellular_component
GO:0005737cytoplasmIEAcellular_component
GO:0005634nucleusISScellular_component
GO:0007267cell-cell signalingIEAbiological_process
GO:0007079mitotic chromosome movement towards spindle poleNASbiological_process
GO:0045842positive regulation of mitotic metaphase/anaphase NASbiological_process
GO:0000087M phase of mitotic cell cycleISSbiological_process