| UniProt/SwissProt ID: | DIAP3_HUMAN |
| Description: | diaphanous homolog 3 (Drosophila) [Source:HGNC Symbol;Acc:15480] |
| Location: | chr13 q21.2 |
| Node attribute: | PPI(source); PPI(target) |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S77 | LDKFAsIRIPG | PhosphoSitePlus | |
| S717 | LKFLDsKIAQN | FH2 | PhosphoSitePlus |
| T19 | GSAAGtPYPSS | PhosphoSitePlus | |
| S1093 | VRQSLsPMSQR | PhosphoSitePlus; HPRD | |
| S624 | LGGQNsPPLPI | PhosphoSitePlus; HPRD | |
| S1096 | SLSPMsQRPVL | PhosphoSitePlus; HPRD | |
| Y673 | VNENKyENVDL | FH2 | PhosphoSitePlus |
| S149 | REKDFsIKKEM | Drf_GBD | PhosphoSitePlus |
| S833 | EEIKKsKSFSK | HPRD | |
| S489 | TRLAEsMIQNL | HPRD | |
| S830 | VRQSLsPMSQR | HPRD | |
| T747 | LEVDEtRLAES | HPRD | |
| S828 | KDVRQsLSPMS | HPRD | |
| S1091 | KDVRQsLSPMS | PhosphoSitePlus; HPRD | |
| S361 | LGGQNsPPLPI | HPRD | |
| S729 | SIFLSsFRVPY | FH2 | PhosphoSitePlus |
| T68 | NIRTLtDDMLD | PhosphoSitePlus | |
| S833 | SLSPMsQRPVL | HPRD | |
| S728 | LSIFLsSFRVP | FH2 | PhosphoSitePlus |
| S752 | TRLAEsMIQNL | HPRD | |
| T66 | HLNIRtLTDDM | PhosphoSitePlus | |
| T484 | LEVDEtRLAES | HPRD | |
| S570 | EEIKKsKSFSK | HPRD | |
| Dephosphorylation site |
| DIAP3_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000383178 | P940S | COSMIC | Ovarian Cancer | 21720365 | ENSP00000383178 | V676L | COSMIC | Head and Neck Cancer | 21984974 | ENSP00000383178 | R172* | COSMIC | Skin Cancer | 21984974 | ENSP00000383178 | F997I | COSMIC | Ovarian Cancer | 21720365 |
| Differential expressed protein |
| DIAP3_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| DIAP3_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| DIAP3_HUMAN | BAIP2_HUMAN | other | KEGG |
| CDC42_HUMAN | DIAP3_HUMAN | other | KEGG |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa04810 | Regulation of actin cytoskeleton |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0016043 | cellular component organization | IEA | biological_process |
| GO:0003779 | actin binding | IEA | molecular_function |
| GO:0005829 | cytosol | IEA | cellular_component |
| GO:0017048 | Rho GTPase binding | IEA | molecular_function |
| GO:0005488 | binding | IEA | molecular_function |
| GO:0030036 | actin cytoskeleton organization | IEA | biological_process |