Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:DIAP3_HUMAN
Description:diaphanous homolog 3 (Drosophila) [Source:HGNC Symbol;Acc:15480]
Location:chr13 q21.2
Node attribute:PPI(source); PPI(target)

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S77LDKFAsIRIPGPhosphoSitePlus
S717LKFLDsKIAQNFH2PhosphoSitePlus
T19GSAAGtPYPSSPhosphoSitePlus
S1093VRQSLsPMSQRPhosphoSitePlus; HPRD
S624LGGQNsPPLPIPhosphoSitePlus; HPRD
S1096SLSPMsQRPVLPhosphoSitePlus; HPRD
Y673VNENKyENVDLFH2PhosphoSitePlus
S149REKDFsIKKEMDrf_GBDPhosphoSitePlus
S833EEIKKsKSFSKHPRD
S489TRLAEsMIQNLHPRD
S830VRQSLsPMSQRHPRD
T747LEVDEtRLAESHPRD
S828KDVRQsLSPMSHPRD
S1091KDVRQsLSPMSPhosphoSitePlus; HPRD
S361LGGQNsPPLPIHPRD
S729SIFLSsFRVPYFH2PhosphoSitePlus
T68NIRTLtDDMLDPhosphoSitePlus
S833SLSPMsQRPVLHPRD
S728LSIFLsSFRVPFH2PhosphoSitePlus
S752TRLAEsMIQNLHPRD
T66HLNIRtLTDDMPhosphoSitePlus
T484LEVDEtRLAESHPRD
S570EEIKKsKSFSKHPRD

Dephosphorylation site
DIAP3_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000383178P940SCOSMICOvarian Cancer21720365
ENSP00000383178V676LCOSMICHead and Neck Cancer21984974
ENSP00000383178R172*COSMICSkin Cancer21984974
ENSP00000383178F997ICOSMICOvarian Cancer21720365

Differential expressed protein
DIAP3_HUMAN is not differential expressed protein.

Hyperphosphorylation site
DIAP3_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
DIAP3_HUMANBAIP2_HUMANotherKEGG
CDC42_HUMANDIAP3_HUMANotherKEGG

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04810Regulation of actin cytoskeleton

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0016043cellular component organizationIEAbiological_process
GO:0003779actin bindingIEAmolecular_function
GO:0005829cytosolIEAcellular_component
GO:0017048Rho GTPase bindingIEAmolecular_function
GO:0005488bindingIEAmolecular_function
GO:0030036actin cytoskeleton organizationIEAbiological_process


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