Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:DERL1_HUMAN
Description:derlin 1 [Source:HGNC Symbol;Acc:28454]
Location:chr8 q24.13
Node attribute:PPI(target)

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S201GRNFLsTPQFLPhosphoSitePlus; HPRD
S218RRGGVsGFGVPPhosphoSitePlus
Y190FLMFRyPMDLGPhosphoSitePlus
S226GVPPAsMRRAAPhosphoSitePlus
T202RNFLStPQFLYPhosphoSitePlus; HPRD; phosphoELM

Dephosphorylation site
DERL1_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000384289S192NBIOMARTPancreatic Cancer21930507, 21930502
ENSP00000259512S212NBIOMARTPancreatic Cancer21930507, 21930502

Differential expressed protein
DERL1_HUMAN is not differential expressed protein.

Hyperphosphorylation site
DERL1_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
SODC_HUMANDERL1_HUMANotherKEGG

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04141Protein processing in endoplasmic reticulum
hsa05014Amyotrophic lateral sclerosis (ALS)

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005515protein bindingIPImolecular_function
GO:0030970retrograde protein transport, ER to cytosolIMPbiological_process
GO:0019060intracellular transport of viral proteins in host TASbiological_process
GO:0045184establishment of protein localizationTASbiological_process
GO:0030433ER-associated protein catabolic processIDAbiological_process
GO:0005770late endosomeIEAcellular_component
GO:0006986response to unfolded proteinIMPbiological_process
GO:0030968endoplasmic reticulum unfolded protein responseIDAbiological_process
GO:0004872receptor activityNASmolecular_function
GO:0005783endoplasmic reticulumIDAcellular_component
GO:0034620cellular response to unfolded proteinIEAbiological_process
GO:0005769early endosomeIEAcellular_component
GO:0042288MHC class I protein bindingIDAmolecular_function
GO:0016021integral to membraneIDAcellular_component
GO:0030176integral to endoplasmic reticulum membraneIDAcellular_component


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