Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:DDIT4_HUMAN
Description:DNA-damage-inducible transcript 4 [Source:HGNC Symbol;Acc:24944]
Location:chr10 q22.1
Node attribute:PPI(source)

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S18TSSSPsSLPRTPhosphoSitePlus

Dephosphorylation site
DDIT4_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000307305G191WCOSMICPancreatic Cancer21252315

Differential expressed protein
DDIT4_HUMAN is not differential expressed protein.

Hyperphosphorylation site
DDIT4_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
DDIT4_HUMANTSC2_HUMANotherKEGG

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04150mTOR signaling pathway

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0001666response to hypoxiaIEAbiological_process
GO:007188914-3-3 protein bindingIEAmolecular_function
GO:0005739mitochondrionIEAcellular_component
GO:0072593reactive oxygen species metabolic processIEAbiological_process
GO:0033137negative regulation of peptidyl-serine phosphorylaISSbiological_process
GO:0042771intrinsic apoptotic signaling pathway in response IEAbiological_process
GO:0032007negative regulation of TOR signaling cascadeIMPbiological_process
GO:0030182neuron differentiationISSbiological_process
GO:0001666response to hypoxiaIDAbiological_process
GO:0009968negative regulation of signal transductionIEAbiological_process
GO:0010801negative regulation of peptidyl-threonine phosphorISSbiological_process
GO:0001764neuron migrationISSbiological_process
GO:0008283cell proliferationISSbiological_process
GO:0007420brain developmentISSbiological_process
GO:1901216positive regulation of neuron deathISSbiological_process
GO:0010741negative regulation of intracellular protein kinasISSbiological_process
GO:0045820negative regulation of glycolysisIEAbiological_process
GO:0048011nerve growth factor receptor signaling pathwayISSbiological_process
GO:0005829cytosolIEAcellular_component
GO:0032007negative regulation of TOR signaling cascadeIEAbiological_process
GO:0042771intrinsic apoptotic signaling pathway in response ISSbiological_process
GO:0043241protein complex disassemblyIEAbiological_process
GO:0005737cytoplasmIDAcellular_component
GO:0051607defense response to virusIEAbiological_process
GO:0005622intracellularIDAcellular_component


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