Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:DAPK2_HUMAN
Description:death-associated protein kinase 2 [Source:HGNC Symbol;Acc:2675]
Location:chr15 q22.31
Node attribute:kinase; substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y49STGLEyAAKFIPkinase; TFIIE_betaPhosphoSitePlus
S318RRWKLsFSIVSDAPK2HPRD; phosphoELM; RegPhos
S318RRWKLsFSIVSautocatalysisRegPhos
S367HPRRRsSTS__PhosphoSitePlus
S368PRRRSsTS___PhosphoSitePlus
S318RRWKLsFSIVSPhosphoSitePlus
S299MVRREsVVNLEPhosphoSitePlus; HPRD
S349LRNCEsDTEEDPhosphoSitePlus; HPRD; phosphoELM; RegPhos; SysPTM

Dephosphorylation site
DAPK2_HUMAN do not have dephosphorylation site.

Mutation site
DAPK2_HUMAN do not have mutation site.

Differential expressed protein
DAPK2_HUMAN is not differential expressed protein.

Hyperphosphorylation site
DAPK2_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
DAPK2_HUMANDAPK2_HUMANkinase -> substrateHPRD; RegPhos
ZAGL2_HUMANDAPK2_HUMANkinase -> substrateRegPhos
AURKB_HUMANDAPK2_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa05219Bladder cancer
hsa05200Pathways in cancer

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0031410cytoplasmic vesicleIEAcellular_component
GO:0006917induction of apoptosisIMPbiological_process
GO:0043276anoikisIMPbiological_process
GO:0005516calmodulin bindingIDAmolecular_function
GO:0042981regulation of apoptotic processTASbiological_process
GO:0004683calmodulin-dependent protein kinase activityTASmolecular_function
GO:0004672protein kinase activityIEAmolecular_function
GO:0042802identical protein bindingIPImolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0016772transferase activity, transferring phosphorus-contIEAmolecular_function
GO:0010506regulation of autophagyTASbiological_process
GO:0046777protein autophosphorylationTASbiological_process
GO:0034423autophagic vacuole lumenIEAcellular_component
GO:0005737cytoplasmIDAcellular_component
GO:0003824catalytic activityIEAmolecular_function
GO:0004713protein tyrosine kinase activityIEAmolecular_function
GO:0007243intracellular protein kinase cascadeIDAbiological_process
GO:0006468protein phosphorylationIDAbiological_process
GO:0004674protein serine/threonine kinase activityTASmolecular_function


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