| UniProt/SwissProt ID: | CXXC4_HUMAN |
| Description: | CXXC finger protein 4 [Source:HGNC Symbol;Acc:24593] |
| Location: | chr4 q24 |
| Node attribute: | PPI(source) |
| Phosphorylation site |
| CXXC4_HUMAN do not have phosphorylation site. |
| Dephosphorylation site |
| CXXC4_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000412267 | I83M | COSMIC | Head and Neck Cancer | 21798893 | ENSP00000412267 | D100N | COSMIC | Head and Neck Cancer | 21798893 | ENSP00000412267 | C50R | COSMIC | Ovarian Cancer | 21720365 |
| Differential expressed protein |
| CXXC4_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| CXXC4_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| CXXC4_HUMAN | DVL1_HUMAN | other | KEGG |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa04310 | Wnt signaling pathway |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0030178 | negative regulation of Wnt receptor signaling path | IDA | biological_process |
| GO:0016055 | Wnt receptor signaling pathway | IEA | biological_process |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0005737 | cytoplasm | IDA | cellular_component |
| GO:0030165 | PDZ domain binding | IPI | molecular_function |
| GO:0008270 | zinc ion binding | IEA | molecular_function |
| GO:0007352 | zygotic specification of dorsal/ventral axis | ISS | biological_process |
| GO:0031410 | cytoplasmic vesicle | IDA | cellular_component |
| GO:0016023 | cytoplasmic membrane-bounded vesicle | IEA | cellular_component |