| UniProt/SwissProt ID: | CXCL6_HUMAN |
| Description: | chemokine (C-X-C motif) ligand 6 [Source:HGNC Symbol;Acc:10643] |
| Location: | chr4 q13.3 |
| Node attribute: | ligand; PPI(source) |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| T62 | RVNPKtIGKLQ | IL8 | PhosphoSitePlus |
| Dephosphorylation site |
| CXCL6_HUMAN do not have dephosphorylation site. |
| Mutation site |
| CXCL6_HUMAN do not have mutation site. |
| Differential expressed protein |
| CXCL6_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| CXCL6_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| CXCL6_HUMAN | CXCR1_HUMAN | ligand -> receptor | HPMR |
| CXCL6_HUMAN | CXCR2_HUMAN | ligand -> receptor | HPMR |
| CXCL6_HUMAN | CXCR2_HUMAN | other | KEGG |
| CXCL6_HUMAN | CXCR1_HUMAN | other | KEGG |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa04062 | Chemokine signaling pathway |
| hsa05323 | Rheumatoid arthritis |
| hsa05133 | Pertussis |
| hsa04060 | Cytokine-cytokine receptor interaction |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0005615 | extracellular space | IEA | cellular_component |
| GO:0006935 | chemotaxis | IEA | biological_process |
| GO:0008201 | heparin binding | IEA | molecular_function |
| GO:0006954 | inflammatory response | TAS | biological_process |
| GO:0006955 | immune response | IEA | biological_process |
| GO:0008009 | chemokine activity | IEA | molecular_function |
| GO:0005576 | extracellular region | TAS | cellular_component |
| GO:0007165 | signal transduction | TAS | biological_process |
| GO:0007267 | cell-cell signaling | TAS | biological_process |