Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:CSF3R_HUMAN
Description:colony stimulating factor 3 receptor (granulocyte) [Source:HGNC Symbol;Acc:2439]
Location:chr1 p34.3
Node attribute:substrate; receptor; PPI(target)

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y779SDQVLyGQLLGHCKHPRD
Y787PSPKSyENLWFPhosphoSitePlus; phosphoELM; RegPhos
Y196KHLLLyQNMGIEpoR_lig-bindPhosphoSitePlus
Y814PSPKSyENLWFHCKHPRD
Y727TLVQTyVLQGDPhosphoSitePlus; phosphoELM; RegPhos
Y767PGPGHyLRCDSPhosphoSitePlus; phosphoELM; RegPhos
S783AGLTPsPKSYEPhosphoSitePlus
Y752SDQVLyGQLLGHCKHPRD; RegPhos
Y752SDQVLyGQLLGPhosphoSitePlus; phosphoELM; RegPhos
T781LLAGLtPSPKSPhosphoSitePlus
Y787PSPKSyENLWFHCKHPRD; RegPhos
T351QLDPRtVQLFWfn3PhosphoSitePlus
S365PLEEDsGRIQGfn3PhosphoSitePlus

Dephosphorylation site
CSF3R_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000362195E480KCOSMICCentral Nervous System Neoplasms18772890
ENSP00000362195E363DCOSMICOvarian Cancer21720365
ENSP00000362195T717MCOSMICCentral Nervous System Neoplasms18772890
ENSP00000362195M696ICOSMICHead and Neck Cancer21798893
ENSP00000362195D172NCOSMICSkin Cancer21984974

Differential expressed protein
CSF3R_HUMAN is not differential expressed protein.

Hyperphosphorylation site
CSF3R_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
CSF2_HUMANCSF3R_HUMANligand -> receptorHPMR
ZAGL2_HUMANCSF3R_HUMANkinase -> substrateRegPhos
HCK_HUMANCSF3R_HUMANkinase -> substrateRegPhos
CSF3_HUMANCSF3R_HUMANotherKEGG

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04060Cytokine-cytokine receptor interaction
hsa05200Pathways in cancer
hsa04630Jak-STAT signaling pathway
hsa04640Hematopoietic cell lineage

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005576extracellular regionIEAcellular_component
GO:0004896cytokine receptor activityIEAmolecular_function
GO:0030593neutrophil chemotaxisIEAbiological_process
GO:0006952defense responseTASbiological_process
GO:0007155cell adhesionIEAbiological_process
GO:0007165signal transductionNASbiological_process
GO:0005887integral to plasma membraneTAScellular_component
GO:0004872receptor activityTASmolecular_function
GO:0042475odontogenesis of dentin-containing toothIEAbiological_process
GO:0005515protein bindingIEAmolecular_function


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