Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:CRTC3_HUMAN
Description:CREB regulated transcription coactivator 3 [Source:HGNC Symbol;Acc:26148]
Location:chr15 q26.1
Node attribute:substrate; TF

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S329LQSSRsNPSIQPhosphoSitePlus; HPRD
S432DRSQLsFLPTEPhosphoSitePlus
T168DSALHtSALSTRegPhos
T160SALNRtNSDSARegPhos
S4GSGSHPRD; SysPTM
S305MSVGNsVNNIPRegPhos
S413QLSSTsPLAPYPhosphoSitePlus
S411SRQLSsTSPLAPhosphoSitePlus; HPRD
S62QYHGGsLPNVSHPRD; RegPhos
S162LNRTNsDSALHTORC_MPhosphoSitePlus
S391RQPPVsPLTLSPhosphoSitePlus; HPRD; RegPhos
T577SLNVDtPFPLETORC_CPhosphoSitePlus
T412RQLSStSPLAPPhosphoSitePlus
S410FSRQLsSTSPLPhosphoSitePlus; HPRD; RegPhos
S4__MAAsPGSGSPhosphoSitePlus; SysPTM
S238EIQSLsGRPRSTORC_MPhosphoSitePlus
S406AHQGFsRQLSSPhosphoSitePlus
S373SLSNPsLSTTNPhosphoSitePlus
Y58LRLTQyHGGSLTORC_NPhosphoSitePlus
S396SPLTLsPGPEAPhosphoSitePlus; HPRD; RegPhos; SysPTM
S443AQAQVsPPPPYPhosphoSitePlus; HPRD; SysPTM
S368SLRLFsLSNPSPhosphoSitePlus
S375SNPSLsTTNLSPhosphoSitePlus
T394PVSPLtLSPGPPhosphoSitePlus; HPRD; RegPhos
S353NHPQTsVPNASPhosphoSitePlus
S344KTVLSsSLNNHPhosphoSitePlus
T455APQELtQPLLQPhosphoSitePlus
S524LVQQGsRELQDPhosphoSitePlus
S129GANYSsQPLDERegPhos
T160SALNRtNSDSATORC_MPhosphoSitePlus
S321LGIRSsSGLQSTORC_MPhosphoSitePlus
S345TVLSSsLNNHPPhosphoSitePlus
S363SALHPsLRLFSPhosphoSitePlus
S62QYHGGsLPNVSTORC_NPhosphoSitePlus
Y448SPPPPyPAPQEPhosphoSitePlus
S370RLFSLsNPSLSPhosphoSitePlus
T352NNHPQtSVPNAPhosphoSitePlus
S305MSVGNsVNNIPTORC_MPhosphoSitePlus
S543YSNCGsLPNTIRegPhos
S162LNRTNsDSALHNuaK2 RegPhos
S135QPLDEsWPRQQPhosphoSitePlus

Dephosphorylation site
CRTC3_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000268184R70QBIOMARTBreast Cancer21930507, 21930502
ENSP00000416573R70QBIOMARTBreast Cancer21930507, 21930502
ENSP00000416573N158KTCGAOvarian Cancer21720365, 18772890
ENSP00000268184*620YCOSMICIntestines Cancer16959974
ENSP00000268184N158KCOSMICOvarian Cancer21720365

Differential expressed protein
CRTC3_HUMAN is not differential expressed protein.

Hyperphosphorylation site
CRTC3_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
ZAGL2_HUMANCRTC3_HUMANkinase -> substrateRegPhos
CRTC3_HUMANIL8_HUMANTF -> target geneTRANSFAC

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa05166HTLV-I infection

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0006351transcription, DNA-dependentIEAbiological_process
GO:0008140cAMP response element binding protein bindingIEAmolecular_function
GO:0051289protein homotetramerizationIEAbiological_process
GO:0005634nucleusIDAcellular_component
GO:0019048virus-host interactionIEAbiological_process
GO:0005737cytoplasmIDAcellular_component
GO:0032793positive regulation of CREB transcription factor aIEAbiological_process


Fatal error: Uncaught Error: Call to undefined function mysql_close() in /usr/local/apache/htdocs/PhoSigNet/include/locateconfig.inc.php:23 Stack trace: #0 /usr/local/apache/htdocs/PhoSigNet/proteintable.php(435): db_disconnect(Object(mysqli)) #1 {main} thrown in /usr/local/apache/htdocs/PhoSigNet/include/locateconfig.inc.php on line 23