Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:CP2C9_HUMAN
Description:cytochrome P450, family 2, subfamily C, polypeptide 9 [Source:HGNC Symbol;Acc:2623]
Location:chr10 q23.33
Node attribute:gene

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S127EIRRFsLMTLRp450PhosphoSitePlus
Y347RSHMPyTDAVVp450PhosphoSitePlus
Y379IKFRNyLIPKGp450PhosphoSitePlus

Dephosphorylation site
CP2C9_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000260682E438KCOSMICHead and Neck Cancer21984974
ENSP00000260682N289SCOSMICMelanoma21499247
ENSP00000260682G442SCOSMICHead and Neck Cancer21798893
ENSP00000260682E444DTCGAOvarian Cancer21720365, 18772890
ENSP00000260682D2NCOSMICMelanoma21499247
ENSP00000260682M1ICOSMICMelanoma21499247
ENSP00000260682E444DCOSMICOvarian Cancer21720365

Differential expressed protein
Ensembl IDCancer nameDesignSampleChangeRatioPubmed
ENSP00000260682hepatitis B virusNormal vs. CancertissueDown0.4514726492

Hyperphosphorylation site
CP2C9_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
HNF4A_HUMANCP2C9_HUMANTF -> target geneTRANSFAC

Function Annotation
KEGG Pathway
CP2C9_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0052741(R)-limonene 6-monooxygenase activityIEAmolecular_function
GO:0042737drug catabolic processIMPbiological_process
GO:0034875caffeine oxidase activityIDAmolecular_function
GO:0042738exogenous drug catabolic processIDAbiological_process
GO:0005789endoplasmic reticulum membraneTAScellular_component
GO:0009055electron carrier activityIEAmolecular_function
GO:0044281small molecule metabolic processTASbiological_process
GO:0018675(S)-limonene 6-monooxygenase activityIEAmolecular_function
GO:0016098monoterpenoid metabolic processIDAbiological_process
GO:0016491oxidoreductase activityIDAmolecular_function
GO:0043231intracellular membrane-bounded organelleTAScellular_component
GO:0032787monocarboxylic acid metabolic processIDAbiological_process
GO:0070989oxidative demethylationIDAbiological_process
GO:0055114oxidation-reduction processIDAbiological_process
GO:0008395steroid hydroxylase activityIMPmolecular_function
GO:0043603cellular amide metabolic processIDAbiological_process
GO:0020037heme bindingIEAmolecular_function
GO:0017144drug metabolic processIDAbiological_process
GO:0018676(S)-limonene 7-monooxygenase activityIEAmolecular_function
GO:0005783endoplasmic reticulumNAScellular_component
GO:0005506iron ion bindingIEAmolecular_function
GO:0008144drug bindingIDAmolecular_function
GO:0019627urea metabolic processIDAbiological_process
GO:0016705oxidoreductase activity, acting on paired donors, IEAmolecular_function
GO:0004497monooxygenase activityIDAmolecular_function
GO:0006805xenobiotic metabolic processTASbiological_process
GO:0008202steroid metabolic processIMPbiological_process


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