Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:CP27A_HUMAN
Description:cytochrome P450, family 27, subfamily A, polypeptide 1 [Source:HGNC Symbol;Acc:2605]
Location:chr2 q35
Node attribute:gene

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y397ETLRLyPVVPTp450PhosphoSitePlus
S321ASGQLsPREAMp450PhosphoSitePlus
S280WNAIFsFGKKLp450PhosphoSitePlus
S321ASGQLsPREAMHPRD

Dephosphorylation site
CP27A_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000258415P302SCOSMICOvarian Cancer21720365
ENSP00000258415*532RCOSMICBreast Cancer20668451
ENSP00000258415P302STCGAOvarian Cancer21720365, 18772890

Differential expressed protein
CP27A_HUMAN is not differential expressed protein.

Hyperphosphorylation site
CP27A_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
HNF4A_HUMANCP27A_HUMANTF -> target geneTRANSFAC

Function Annotation
KEGG Pathway
CP27A_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0044281small molecule metabolic processTASbiological_process
GO:0006699bile acid biosynthetic processTASbiological_process
GO:0031073cholesterol 26-hydroxylase activityIEAmolecular_function
GO:0047749cholestanetriol 26-monooxygenase activityIEAmolecular_function
GO:0016705oxidoreductase activity, acting on paired donors, IEAmolecular_function
GO:0005759mitochondrial matrixTAScellular_component
GO:0005739mitochondrionIEAcellular_component
GO:0005506iron ion bindingIEAmolecular_function
GO:0055114oxidation-reduction processIEAbiological_process
GO:0020037heme bindingIEAmolecular_function
GO:0005743mitochondrial inner membraneIEAcellular_component
GO:0030343vitamin D3 25-hydroxylase activityIEAmolecular_function
GO:0006805xenobiotic metabolic processTASbiological_process
GO:0008395steroid hydroxylase activityTASmolecular_function
GO:0008206bile acid metabolic processTASbiological_process
GO:0005740mitochondrial envelopeIEAcellular_component
GO:0009055electron carrier activityIEAmolecular_function
GO:0008203cholesterol metabolic processIEAbiological_process


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