Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:COR1B_HUMAN
Description:coronin, actin binding protein, 1B [Source:HGNC Symbol;Acc:2253]
Location:chr11 q13.2
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y26KNDQCyEDIRVDUF1899PhosphoSitePlus
S413RRNVLsDSRPAHPRD
S199ACKDKsVRIIDWD40PhosphoSitePlus
S2RKVVPRKCAHPRD
S2____MsFRKVVPhosphoSitePlus
S2MSFRKvVPKCaRegPhos
S2MSFRKvVPKC_groupRegPhos
S66LVLPLsKTGRIDUF1899PhosphoSitePlus
T209DPRRGtLVAERPhosphoSitePlus
T439TAADAtPSGSLPhosphoSitePlus
S381AEEWVsGRDADHPRD

Dephosphorylation site
COR1B_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000340211V411MSjoblom2006, COSMICIntestines Cancer16959974
ENSP00000377471V411MHPIColorectal Cancer16959974
ENSP00000377471V411MSjoblom2006Intestines Cancer16959974
ENSP00000340211V411MHPIColorectal Cancer16959974
ENSP00000340211R33CCOSMICOvarian Cancer21720365

Differential expressed protein
Ensembl IDCancer nameDesignSampleChangeRatioPubmed
ENSP00000377471Breast CancerTreatment (tamoxifen-sensitive vs. tamoxifen-resistant)tissueUp2.419329653

Hyperphosphorylation site
COR1B_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
KPCA_HUMANCOR1B_HUMANkinase -> substrateHPRD

Function Annotation
KEGG Pathway
COR1B_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0015629actin cytoskeletonIBAcellular_component
GO:0005515protein bindingIEAmolecular_function
GO:0005515protein bindingIPImolecular_function
GO:0051015actin filament bindingIBAmolecular_function
GO:0005737cytoplasmIEAcellular_component
GO:0030036actin cytoskeleton organizationIBAbiological_process


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