| UniProt/SwissProt ID: | COIL_HUMAN |
| Description: | coilin [Source:HGNC Symbol;Acc:2184] |
| Location: | chr17 q22 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S566 | RLIIEsPSNTS | PhosphoSitePlus; HPRD; phosphoELM | |
| S486 | LLELTsSYSPD | HPRD | |
| T39 | RCRVVtDLISL | PhosphoSitePlus | |
| S271 | LEARNsSEKLP | PhosphoSitePlus; HPRD; phosphoELM | |
| T303 | LGFSLtPSKGK | PhosphoSitePlus; HPRD; phosphoELM | |
| S571 | SPSNTsSTE | HPRD | |
| S272 | EARNSsEKLPT | PhosphoSitePlus; HPRD | |
| S568 | IIESPsNTSST | HPRD | |
| T456 | QNPVEtPKKDY | PhosphoSitePlus; HPRD; phosphoELM | |
| S572 | PSNTSsTE | HPRD | |
| Y128 | EPDCKySKKHW | PhosphoSitePlus | |
| S105 | GDINLsLRKAK | PhosphoSitePlus; HPRD | |
| S43 | VTDLIsLIRQR | PhosphoSitePlus | |
| S226 | GSARNsLVKAK | PhosphoSitePlus | |
| T573 | SNTSStEPA__ | PhosphoSitePlus | |
| S403 | EENLFsWKGAK | PhosphoSitePlus; HPRD | |
| S184 | EAKRKsPKKKE | CDK2 | HPRD; phosphoELM |
| S301 | IKLGFsLTPSK | PhosphoSitePlus; HPRD; phosphoELM | |
| S129 | PDCKYsKKHWK | PhosphoSitePlus | |
| T122 | EEGEEtEPDCK | PhosphoSitePlus; HPRD; phosphoELM | |
| S462 | PKKDYsLLPLL | PhosphoSitePlus; HPRD; phosphoELM | |
| S571 | SPSNTsSTEPA | PhosphoSitePlus | |
| T277 | SEKLPtELSKE | HPRD | |
| S202 | AKNPKsPKVQA | PhosphoSitePlus; HPRD; phosphoELM | |
| S184 | EAKRKsPKKKE | PhosphoSitePlus | |
| T290 | STKNTtADKLA | PhosphoSitePlus; HPRD; phosphoELM | |
| T573 | SNTSStE | HPRD | |
| Y488 | ELTSSySPDVS | HPRD | |
| S487 | LELTSsYSPDV | HPRD; phosphoELM | |
| S489 | LTSSYsPDVSD | PhosphoSitePlus; HPRD; phosphoELM | |
| T570 | ESPSNtSSTE | HPRD | |
| Dephosphorylation site |
| COIL_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000240316 | L148V | BIOMART | Breast Cancer | 21930507, 21930502 |
| Differential expressed protein |
| COIL_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| COIL_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| CDK2_HUMAN | COIL_HUMAN | kinase -> substrate | HPRD; RegPhos |
| ZAGL2_HUMAN | COIL_HUMAN | kinase -> substrate | RegPhos |
| Function Annotation |
| KEGG Pathway |
| COIL_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0008022 | protein C-terminus binding | IPI | molecular_function |
| GO:0005515 | protein binding | IPI | molecular_function |
| GO:0005654 | nucleoplasm | IDA | cellular_component |
| GO:0001674 | female germ cell nucleus | IEA | cellular_component |
| GO:0015030 | Cajal body | IDA | cellular_component |
| GO:0005634 | nucleus | TAS | cellular_component |
| GO:0042802 | identical protein binding | IPI | molecular_function |
| GO:0005730 | nucleolus | IDA | cellular_component |
| GO:0015030 | Cajal body | IEA | cellular_component |
| GO:0015036 | disulfide oxidoreductase activity | IEA | molecular_function |