Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:COE1_HUMAN
Description:early B-cell factor 1 [Source:HGNC Symbol;Acc:3126]
Location:chr5 q33.3
Node attribute:TF

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y412IAEALySVPRNPhosphoSitePlus

Dephosphorylation site
COE1_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000370029R129HBIOMARTBreast Cancer21930507, 21930502
ENSP00000322898A495TCOSMICHead and Neck Cancer21798893
ENSP00000322898R129HBIOMARTBreast Cancer21930507, 21930502
ENSP00000322898R242QCOSMICPancreatic Cancer

Differential expressed protein
COE1_HUMAN is not differential expressed protein.

Hyperphosphorylation site
COE1_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
COE1_HUMANCD79A_HUMANTF -> target geneTRANSFAC
COE1_HUMANIGLL1_HUMANTF -> target geneTRANSFAC
COE1_HUMANVPREB_HUMANTF -> target geneTRANSFAC

Function Annotation
KEGG Pathway
COE1_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0006351transcription, DNA-dependentIEAbiological_process
GO:0005634nucleusIEAcellular_component
GO:0003677DNA bindingIEAmolecular_function
GO:0046983protein dimerization activityIEAmolecular_function
GO:0006355regulation of transcription, DNA-dependentIEAbiological_process
GO:0007275multicellular organismal developmentIEAbiological_process
GO:0003700sequence-specific DNA binding transcription factorIEAmolecular_function
GO:0005515protein bindingIEAmolecular_function
GO:0046872metal ion bindingIEAmolecular_function
GO:0045893positive regulation of transcription, DNA-dependenIEAbiological_process


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