| UniProt/SwissProt ID: | CO5A3_HUMAN |
| Description: | collagen, type V, alpha 3 [Source:HGNC Symbol;Acc:14864] |
| Location: | chr19 p13.2 |
| Node attribute: | ligand |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| T1684 | LSFNQtTAATV | COLFI | PhosphoSitePlus |
| S718 | GVKGTsGNRGL | PhosphoSitePlus; HPRD; phosphoELM | |
| Y110 | VLLSIyDERGA | PhosphoSitePlus | |
| T1685 | SFNQTtAATVS | COLFI | PhosphoSitePlus |
| S1315 | GKRGPsGHMGR | Collagen | PhosphoSitePlus |
| Dephosphorylation site |
| CO5A3_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000264828 | G545R | COSMIC | Skin Cancer | 21984974 | ENSP00000264828 | G1118A | COSMIC | Ovarian Cancer | 21720365 | ENSP00000264828 | G1157R | COSMIC | Ovarian Cancer | 21720365 | ENSP00000264828 | G518E | COSMIC | Ovarian Cancer | 21720365 | ENSP00000264828 | A846V | COSMIC | Ovarian Cancer | 21720365 | ENSP00000264828 | G1064R | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000264828 | P1438S | COSMIC | Skin Cancer | 21984974 | ENSP00000264828 | G776A | COSMIC | Ovarian Cancer | 21720365 | ENSP00000264828 | R245W | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000264828 | G1190V | COSMIC | Ovarian Cancer | 21720365 | ENSP00000264828 | D859N | COSMIC | Skin Cancer | 21984974 |
| Differential expressed protein |
| CO5A3_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| CO5A3_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| CO5A3_HUMAN | SDC3_HUMAN | ligand -> receptor | HPMR |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa05146 | Amoebiasis |
| hsa04510 | Focal adhesion |
| hsa04512 | ECM-receptor interaction |
| hsa04974 | Protein digestion and absorption |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0031012 | extracellular matrix | IEA | cellular_component |
| GO:0005588 | collagen type V | NAS | cellular_component |
| GO:0005588 | collagen type V | IEA | cellular_component |
| GO:0043394 | proteoglycan binding | IEA | molecular_function |
| GO:0030199 | collagen fibril organization | NAS | biological_process |
| GO:0005576 | extracellular region | TAS | cellular_component |
| GO:0005788 | endoplasmic reticulum lumen | TAS | cellular_component |
| GO:0005201 | extracellular matrix structural constituent | NAS | molecular_function |
| GO:0005581 | collagen | IEA | cellular_component |
| GO:0030198 | extracellular matrix organization | TAS | biological_process |
| GO:0007160 | cell-matrix adhesion | IEA | biological_process |
| GO:0043588 | skin development | NAS | biological_process |
| GO:0005518 | collagen binding | NAS | molecular_function |
| GO:0008201 | heparin binding | IEA | molecular_function |