Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:CNKR1_HUMAN
Description:connector enhancer of kinase suppressor of Ras 1 [Source:HGNC Symbol;Acc:19700]
Location:chr1 p36.11
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S300PQVLDsPHQRSPhosphoSitePlus
S307HQRSPsLSLAPPhosphoSitePlus; phosphoELM
S300HQRSPsLSLAPHPRD
S307SLAPLsPRAPSHPRD
T289IPIPEtPPQTPPhosphoSitePlus
S314SLAPLsPRAPSPhosphoSitePlus; phosphoELM; SysPTM
S278EPAGLsLVLKKPhosphoSitePlus
S305SPHQRsPSLSLPhosphoSitePlus; phosphoELM
Y456INVSNySLESGPHPhosphoSitePlus
T293ETPPQtPPQVLPhosphoSitePlus
S298SPHQRsPSLSLHPRD
S385LATRLsRRRVSNME1HPRD

Dephosphorylation site
CNKR1_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000354609W486*COSMICOvarian Cancer21720365
ENSP00000354609A503TCOSMICHead and Neck Cancer21798893
ENSP00000354609H687YCOSMICRenal Cancer20054297

Differential expressed protein
CNKR1_HUMAN is not differential expressed protein.

Hyperphosphorylation site
CNKR1_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
NDKA_HUMANCNKR1_HUMANkinase -> substrateHPRD

Function Annotation
KEGG Pathway
CNKR1_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005938cell cortexIDAcellular_component
GO:0007265Ras protein signal transductionIPIbiological_process
GO:0007169transmembrane receptor protein tyrosine kinase sigTASbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0007266Rho protein signal transductionIPIbiological_process
GO:0005911cell-cell junctionTAScellular_component
GO:0016301kinase activityIEAmolecular_function
GO:0005886plasma membraneTAScellular_component
GO:0005543phospholipid bindingIEAmolecular_function
GO:0030674protein binding, bridgingIDAmolecular_function


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