Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:CND1_HUMAN
Description:non-SMC condensin I complex, subunit D2 [Source:HGNC Symbol;Acc:24305]
Location:chr12 p13.31
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
T1345PEPRRtTRRHPPhosphoSitePlus
S1330YQPLAsTASDNPhosphoSitePlus; HPRD; phosphoELM; RegPhos
T1388ETPKKtTPILRPhosphoSitePlus; HPRD; phosphoELM; RegPhos; SysPTM
S973EKNTSsETTMEHPRD; phosphoELM
T1389TPKKTtPILRAPhosphoSitePlus; HPRD; phosphoELM
T1384MTEDEtPKKTTCDC2 RegPhos
S1366PKVVFsSDESSPhosphoSitePlus; HPRD; phosphoELM; RegPhos
T1389TPKKTtPILRACDC2 RegPhos
S1371SSDESsEEDLSPhosphoSitePlus; HPRD; phosphoELM; RegPhos
Y6MAPQMyEFHLPPhosphoSitePlus
S1333LASTAsDNDFVPhosphoSitePlus; HPRD; phosphoELM; RegPhos; SysPTM
S291CPQELsRDPSGPhosphoSitePlus
T1352RRHPNtQQRASPhosphoSitePlus
S1395PILRAsARRHRPhosphoSitePlus
S1367KVVFSsDESSEPhosphoSitePlus; HPRD; phosphoELM; RegPhos
T1094LVDPWtPHLYACnd1PhosphoSitePlus
S378GHDVNsFVRSRHPRD
T1339DNDFVtPEPRRPhosphoSitePlus; HPRD; phosphoELM; SysPTM
T1380LSAEMtEDETPHPRD
T454PLQKEtQKLQEPhosphoSitePlus
T154GKKARtKAAHGCnd1_NPhosphoSitePlus
Y1325STGSRyQPLASPhosphoSitePlus; HPRD
S1376SEEDLsAEMTEPhosphoSitePlus; HPRD; phosphoELM; RegPhos
T976TSSETtMEEELHPRD; phosphoELM
T103AILDDtTLSGSphosphoELM; RegPhos; SysPTM
S13FHLPLsPEELLPhosphoSitePlus; HPRD
Y1228QRDLAyCVSQLCnd1PhosphoSitePlus
S1370FSSDEsSEEDLPhosphoSitePlus; HPRD; phosphoELM; RegPhos
S20EELLKsGGVNQPhosphoSitePlus; HPRD
T103AILDDtTLSGSCnd1_NPhosphoSitePlus; SysPTM
S576KGPAAsTQEKNPhosphoSitePlus
S1310IGQAGsQRAPSPhosphoSitePlus; HPRD; phosphoELM; RegPhos
T1331QPLAStASDNDPhosphoSitePlus; HPRD; phosphoELM; RegPhos
T1339DNDFVtPEPRRCDC2 RegPhos; SysPTM
T1061LRLLFtMLEKSPhosphoSitePlus; HPRD
T1384MTEDEtPKKTTHPRD
S585KNPREsTGNMVPhosphoSitePlus; HPRD; phosphoELM; RegPhos; SysPTM
T577GPAAStQEKNPPhosphoSitePlus; HPRD; phosphoELM; RegPhos
T586NPREStGNMVTPhosphoSitePlus; HPRD; phosphoELM

Dephosphorylation site
CND1_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000325017E762KBIOMARTBreast Cancer21930507, 21930502
ENSP00000325017R698CCOSMICRenal Cancer20054297
ENSP00000325017D802ECOSMICOvarian Cancer21720365
ENSP00000325017R838QCOSMICHead and Neck Cancer21984974
ENSP00000325017S188*COSMICHead and Neck Cancer21798893
ENSP00000325017S1258YCOSMICHead and Neck Cancer21798893
ENSP00000325017R1343CBIOMARTBreast Cancer21930507, 21930502

Differential expressed protein
Ensembl IDCancer nameDesignSampleChangeRatioPubmed
ENSP00000325017Hepatocellular CarcinomaNormal vs. Cancercell lineDown0.4218646787
ENSP00000325017Testicular CancerNormal vs. Cancercell lineUp18489135

Hyperphosphorylation site
CND1_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
ZAGL2_HUMANCND1_HUMANkinase -> substrateRegPhos

Function Annotation
KEGG Pathway
CND1_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0006886intracellular protein transportIEAbiological_process
GO:0042393histone bindingNASmolecular_function
GO:0000793condensed chromosomeIEAcellular_component
GO:0005737cytoplasmIDAcellular_component
GO:0000228nuclear chromosomeIDAcellular_component
GO:0030117membrane coatIEAcellular_component
GO:0007076mitotic chromosome condensationIEAbiological_process
GO:0005488bindingIEAmolecular_function
GO:0000797condensin core heterodimerNAScellular_component
GO:0045120pronucleusIEAcellular_component
GO:0005515protein bindingIPImolecular_function
GO:0005634nucleusIDAcellular_component
GO:0000796condensin complexIDAcellular_component
GO:0051301cell divisionIEAbiological_process
GO:0016192vesicle-mediated transportIEAbiological_process
GO:0030261chromosome condensationIEAbiological_process
GO:0007067mitosisIEAbiological_process


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