Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:CLD3_HUMAN
Description:claudin 3 [Source:HGNC Symbol;Acc:2045]
Location:chr7 q11.23
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
T194KKYTAtKVVYSPhosphoSitePlus
Y219YDRKDyV____PhosphoSitePlus
T192REKKYtATKVVPRKACAHPRD
T192REKKYtATKVVPhosphoSitePlus
Y219YDRKDHPRD; phosphoELM
Y191PREKKyTATKVPhosphoSitePlus
Y198ATKVVySAPRSPhosphoSitePlus
T212GASLGtGYDRKPhosphoSitePlus
S203YSAPRsTGPGAPhosphoSitePlus; HPRD
T192REKKYtATKVVPKACaRegPhos
Y214SLGTGyDRKDYPhosphoSitePlus
T204SAPRStGPGASPhosphoSitePlus; RegPhos
S209TGPGAsLGTGYPhosphoSitePlus
S199TKVVYsAPRSTPhosphoSitePlus
Y214SLGTGyDRKDHPRD; phosphoELM

Dephosphorylation site
CLD3_HUMAN do not have dephosphorylation site.

Mutation site
CLD3_HUMAN do not have mutation site.

Differential expressed protein
CLD3_HUMAN is not differential expressed protein.

Hyperphosphorylation site
CLD3_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
ZAGL2_HUMANCLD3_HUMANkinase -> substrateRegPhos
KPCA_HUMANCLD3_HUMANkinase -> substrateHPRD

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04514Cell adhesion molecules (CAMs)
hsa04530Tight junction
hsa05160Hepatitis C
hsa04670Leukocyte transendothelial migration

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0016338calcium-independent cell-cell adhesionIEAbiological_process
GO:0005887integral to plasma membraneTAScellular_component
GO:0001666response to hypoxiaIEPbiological_process
GO:0005198structural molecule activityIEAmolecular_function
GO:0016021integral to membraneTAScellular_component
GO:0042802identical protein bindingIEAmolecular_function
GO:0005923tight junctionIEAcellular_component
GO:0016020membraneIEAcellular_component
GO:0004888transmembrane signaling receptor activityTASmolecular_function
GO:0005515protein bindingIEAmolecular_function


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