| UniProt/SwissProt ID: | CLD3_HUMAN |
| Description: | claudin 3 [Source:HGNC Symbol;Acc:2045] |
| Location: | chr7 q11.23 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| T194 | KKYTAtKVVYS | PhosphoSitePlus | |
| Y219 | YDRKDyV____ | PhosphoSitePlus | |
| T192 | REKKYtATKVV | PRKACA | HPRD |
| T192 | REKKYtATKVV | PhosphoSitePlus | |
| Y219 | YDRKD | HPRD; phosphoELM | |
| Y191 | PREKKyTATKV | PhosphoSitePlus | |
| Y198 | ATKVVySAPRS | PhosphoSitePlus | |
| T212 | GASLGtGYDRK | PhosphoSitePlus | |
| S203 | YSAPRsTGPGA | PhosphoSitePlus; HPRD | |
| T192 | REKKYtATKVV | PKACa | RegPhos |
| Y214 | SLGTGyDRKDY | PhosphoSitePlus | |
| T204 | SAPRStGPGAS | PhosphoSitePlus; RegPhos | |
| S209 | TGPGAsLGTGY | PhosphoSitePlus | |
| S199 | TKVVYsAPRST | PhosphoSitePlus | |
| Y214 | SLGTGyDRKD | HPRD; phosphoELM | |
| Dephosphorylation site |
| CLD3_HUMAN do not have dephosphorylation site. |
| Mutation site |
| CLD3_HUMAN do not have mutation site. |
| Differential expressed protein |
| CLD3_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| CLD3_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| ZAGL2_HUMAN | CLD3_HUMAN | kinase -> substrate | RegPhos |
| KPCA_HUMAN | CLD3_HUMAN | kinase -> substrate | HPRD |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa04514 | Cell adhesion molecules (CAMs) |
| hsa04530 | Tight junction |
| hsa05160 | Hepatitis C |
| hsa04670 | Leukocyte transendothelial migration |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0016338 | calcium-independent cell-cell adhesion | IEA | biological_process |
| GO:0005887 | integral to plasma membrane | TAS | cellular_component |
| GO:0001666 | response to hypoxia | IEP | biological_process |
| GO:0005198 | structural molecule activity | IEA | molecular_function |
| GO:0016021 | integral to membrane | TAS | cellular_component |
| GO:0042802 | identical protein binding | IEA | molecular_function |
| GO:0005923 | tight junction | IEA | cellular_component |
| GO:0016020 | membrane | IEA | cellular_component |
| GO:0004888 | transmembrane signaling receptor activity | TAS | molecular_function |
| GO:0005515 | protein binding | IEA | molecular_function |