Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:CHRD_HUMAN
Description:chordin [Source:HGNC Symbol;Acc:1949]
Location:chr3 q27.1
Node attribute:PPI(source)

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S132QERSSsERQPSPhosphoSitePlus
S130CPQERsSSERQPhosphoSitePlus
T942RPAPEtRTDPEHPRD
S131PQERSsSERQPPhosphoSitePlus

Dephosphorylation site
CHRD_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000204604P801LCOSMICMelanoma21499247
ENSP00000204604G513RTCGAOvarian Cancer21720365, 18772890
ENSP00000204604P511LCOSMICSkin Cancer21984974
ENSP00000204604G513RCOSMICOvarian Cancer21720365

Differential expressed protein
CHRD_HUMAN is not differential expressed protein.

Hyperphosphorylation site
CHRD_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
CHRD_HUMANGDF7_HUMANotherKEGG

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04350TGF-beta signaling pathway

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0030514negative regulation of BMP signaling pathwayIEAbiological_process
GO:0030514negative regulation of BMP signaling pathwayIMPbiological_process
GO:0005615extracellular spaceIEAcellular_component
GO:0001707mesoderm formationIEAbiological_process
GO:0001501skeletal system developmentIEAbiological_process
GO:0021919BMP signaling pathway involved in spinal cord dorsIMPbiological_process
GO:0001702gastrulation with mouth forming secondIEAbiological_process
GO:0030900forebrain developmentIEAbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0009953dorsal/ventral pattern formationIEAbiological_process
GO:0001649osteoblast differentiationIEAbiological_process
GO:0007389pattern specification processIEAbiological_process
GO:0030336negative regulation of cell migrationIDAbiological_process
GO:0033504floor plate developmentTASbiological_process
GO:0019955cytokine bindingNASmolecular_function
GO:0005615extracellular spaceNAScellular_component
GO:0045545syndecan bindingIEAmolecular_function
GO:0002053positive regulation of mesenchymal cell proliferatIMPbiological_process
GO:0001501skeletal system developmentTASbiological_process
GO:0045785positive regulation of cell adhesionIDAbiological_process
GO:0008201heparin bindingIEAmolecular_function
GO:0007417central nervous system developmentIEAbiological_process
GO:0045668negative regulation of osteoblast differentiationIMPbiological_process
GO:0045668negative regulation of osteoblast differentiationIEAbiological_process


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