| UniProt/SwissProt ID: | CDK17_HUMAN |
| Description: | cyclin-dependent kinase 17 [Source:HGNC Symbol;Acc:8750] |
| Location: | chr12 q23.1 |
| Node attribute: | kinase; substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| Y203 | LGEGTyATVYK | Pkinase | PhosphoSitePlus |
| S137 | IHRRIsMEDLN | CDK17 | HPRD |
| T124 | EVQSPtGVCLR | HPRD | |
| T205 | EGTYAtVYKGR | Pkinase | PhosphoSitePlus |
| S182 | RRASLsEIGFG | PhosphoSitePlus | |
| Y207 | TYATVyKGRSK | Pkinase | PhosphoSitePlus |
| S122 | SDEVQsPTGVC | PhosphoSitePlus; HPRD | |
| S75 | LRRPHsVIGGS | PhosphoSitePlus | |
| S444 | APRLDsEGIEL | HPRD | |
| S109 | GSDGEsDQASG | HPRD | |
| S9 | FKRRLsLTLRG | PhosphoSitePlus; phosphoELM | |
| S520 | KNRRQsMLF__ | PhosphoSitePlus | |
| S180 | RSRRAsLSEIG | PhosphoSitePlus; phosphoELM | |
| S444 | APRLDsEGIEL | Pkinase | PhosphoSitePlus |
| S9 | FKRRLsLTLRG | CDK17 | HPRD |
| S146 | LNKRLsLPADI | PhosphoSitePlus; phosphoELM | |
| T205 | EGTYAtVYKGR | HPRD | |
| S491 | SVSIFsLKEIQ | PhosphoSitePlus | |
| S520 | KNRRQsM | HPRD | |
| S105 | NLKMGsDGESD | PhosphoSitePlus; HPRD | |
| S137 | IHRRIsMEDLN | PhosphoSitePlus; phosphoELM | |
| S92 | MPRNGsRLDIV | PhosphoSitePlus | |
| Y203 | LGEGTyATVYK | HPRD; phosphoELM | |
| S180 | RSRRAsLSEIG | CDK17 | HPRD |
| S146 | LNKRLsLPADI | CDK17 | HPRD |
| S165 | KLQINsPPFDQ | PhosphoSitePlus; HPRD; phosphoELM | |
| S80 | SVIGGsLGSFM | PhosphoSitePlus | |
| T202 | KLGEGtYATVY | Pkinase | PhosphoSitePlus |
| T202 | KLGEGtYATVY | HPRD | |
| S176 | PMSRRsRRASL | PhosphoSitePlus | |
| S64 | HQYTGsFKKPP | PhosphoSitePlus | |
| Dephosphorylation site |
| CDK17_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000261211 | I77N | Ding2008, BIOMART | Lung Cancer | 18948947, 21930507, 21930502 | ENSP00000261211 | R312G | Ding2008, BIOMART | Lung Cancer | 18948947, 21930507, 21930502 |
| Differential expressed protein |
| CDK17_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| CDK17_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| CDK17_HUMAN | CDK17_HUMAN | kinase -> substrate | HPRD |
| Function Annotation |
| KEGG Pathway |
| CDK17_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0006468 | protein phosphorylation | TAS | biological_process |
| GO:0004672 | protein kinase activity | TAS | molecular_function |
| GO:0004713 | protein tyrosine kinase activity | IEA | molecular_function |
| GO:0016772 | transferase activity, transferring phosphorus-cont | IEA | molecular_function |
| GO:0004693 | cyclin-dependent protein kinase activity | IEA | molecular_function |
| GO:0004674 | protein serine/threonine kinase activity | IEA | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |