Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:CDK17_HUMAN
Description:cyclin-dependent kinase 17 [Source:HGNC Symbol;Acc:8750]
Location:chr12 q23.1
Node attribute:kinase; substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y203LGEGTyATVYKPkinasePhosphoSitePlus
S137IHRRIsMEDLNCDK17HPRD
T124EVQSPtGVCLRHPRD
T205EGTYAtVYKGRPkinasePhosphoSitePlus
S182RRASLsEIGFGPhosphoSitePlus
Y207TYATVyKGRSKPkinasePhosphoSitePlus
S122SDEVQsPTGVCPhosphoSitePlus; HPRD
S75LRRPHsVIGGSPhosphoSitePlus
S444APRLDsEGIELHPRD
S109GSDGEsDQASGHPRD
S9FKRRLsLTLRGPhosphoSitePlus; phosphoELM
S520KNRRQsMLF__PhosphoSitePlus
S180RSRRAsLSEIGPhosphoSitePlus; phosphoELM
S444APRLDsEGIELPkinasePhosphoSitePlus
S9FKRRLsLTLRGCDK17HPRD
S146LNKRLsLPADIPhosphoSitePlus; phosphoELM
T205EGTYAtVYKGRHPRD
S491SVSIFsLKEIQPhosphoSitePlus
S520KNRRQsMHPRD
S105NLKMGsDGESDPhosphoSitePlus; HPRD
S137IHRRIsMEDLNPhosphoSitePlus; phosphoELM
S92MPRNGsRLDIVPhosphoSitePlus
Y203LGEGTyATVYKHPRD; phosphoELM
S180RSRRAsLSEIGCDK17HPRD
S146LNKRLsLPADICDK17HPRD
S165KLQINsPPFDQPhosphoSitePlus; HPRD; phosphoELM
S80SVIGGsLGSFMPhosphoSitePlus
T202KLGEGtYATVYPkinasePhosphoSitePlus
T202KLGEGtYATVYHPRD
S176PMSRRsRRASLPhosphoSitePlus
S64HQYTGsFKKPPPhosphoSitePlus

Dephosphorylation site
CDK17_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000261211I77NDing2008, BIOMARTLung Cancer18948947, 21930507, 21930502
ENSP00000261211R312GDing2008, BIOMARTLung Cancer18948947, 21930507, 21930502

Differential expressed protein
CDK17_HUMAN is not differential expressed protein.

Hyperphosphorylation site
CDK17_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
CDK17_HUMANCDK17_HUMANkinase -> substrateHPRD

Function Annotation
KEGG Pathway
CDK17_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0006468protein phosphorylationTASbiological_process
GO:0004672protein kinase activityTASmolecular_function
GO:0004713protein tyrosine kinase activityIEAmolecular_function
GO:0016772transferase activity, transferring phosphorus-contIEAmolecular_function
GO:0004693cyclin-dependent protein kinase activityIEAmolecular_function
GO:0004674protein serine/threonine kinase activityIEAmolecular_function
GO:0005524ATP bindingIEAmolecular_function


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