Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:CDK15_HUMAN
Description:cyclin-dependent kinase 15 [Source:HGNC Symbol;Acc:14434]
Location:chr2 q33.1
Node attribute:kinase

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y118SYATVyKGISRPkinasePhosphoSitePlus
Y63LGEGSyATVYKHPRD
Y114LGEGSyATVYKPkinasePhosphoSitePlus
Y67SYATVyKGISRHPRD

Dephosphorylation site
CDK15_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000386901V210MTCGAOvarian Cancer21720365, 18772890
ENSP00000386901E225DGreenman2007Breast Cancer17344846
ENSP00000260967F243LDing2008, BIOMARTLung Cancer18948947, 21930507, 21930502
ENSP00000386901K42EGreenman2007Renal Cancer17344846
ENSP00000260967V210MTCGAOvarian Cancer21720365, 18772890
ENSP00000260967K42EGreenman2007Renal Cancer17344846
ENSP00000260967E225DGreenman2007Breast Cancer17344846

Differential expressed protein
CDK15_HUMAN is not differential expressed protein.

Hyperphosphorylation site
CDK15_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
CDK15_HUMANCBL_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
CDK15_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0016772transferase activity, transferring phosphorus-contIEAmolecular_function
GO:0046872metal ion bindingIEAmolecular_function
GO:0004672protein kinase activityIEAmolecular_function
GO:0005515protein bindingIPImolecular_function
GO:0004713protein tyrosine kinase activityIEAmolecular_function
GO:0006468protein phosphorylationIEAbiological_process
GO:0004693cyclin-dependent protein kinase activityIEAmolecular_function
GO:0005524ATP bindingIEAmolecular_function


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