Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:CD8A_HUMAN
Description:CD8a molecule [Source:HGNC Symbol;Acc:1706]
Location:chr2 p11.2
Node attribute:PPI(target); gene

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S229SGDKPsLSARYPhosphoSitePlus
S231DKPSLsARYV_PhosphoSitePlus
S224RPVVKsGDKPSPhosphoSitePlus

Dephosphorylation site
CD8A_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000283635D104NCOSMICOvarian Cancer21720365

Differential expressed protein
CD8A_HUMAN is not differential expressed protein.

Hyperphosphorylation site
CD8A_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
1A80_HUMANCD8A_HUMANotherKEGG
ETS1_HUMANCD8A_HUMANTF -> target geneTRANSFAC
IKZF1_HUMANCD8A_HUMANTF -> target geneTRANSFAC

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04640Hematopoietic cell lineage
hsa04514Cell adhesion molecules (CAMs)
hsa05340Primary immunodeficiency
hsa04612Antigen processing and presentation
hsa04660T cell receptor signaling pathway

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005886plasma membraneTAScellular_component
GO:0051607defense response to virusIEAbiological_process
GO:0005576extracellular regionIEAcellular_component
GO:0015026coreceptor activityNASmolecular_function
GO:0002456T cell mediated immunityIEAbiological_process
GO:0042101T cell receptor complexNAScellular_component
GO:0005515protein bindingIPImolecular_function
GO:0045065cytotoxic T cell differentiationIEAbiological_process
GO:0005887integral to plasma membraneNAScellular_component
GO:0050776regulation of immune responseTASbiological_process
GO:0042803protein homodimerization activityIEAmolecular_function
GO:0007169transmembrane receptor protein tyrosine kinase sigNASbiological_process
GO:0007166cell surface receptor signaling pathwayIEAbiological_process
GO:0009986cell surfaceIEAcellular_component
GO:0006955immune responseNASbiological_process
GO:0009897external side of plasma membraneIEAcellular_component
GO:0042288MHC class I protein bindingNASmolecular_function
GO:0042110T cell activationNASbiological_process
GO:0009897external side of plasma membraneIDAcellular_component
GO:0019901protein kinase bindingIEAmolecular_function
GO:0050850positive regulation of calcium-mediated signalingIEAbiological_process
GO:0042110T cell activationIEAbiological_process
GO:0019882antigen processing and presentationNASbiological_process


Fatal error: Uncaught Error: Call to undefined function mysql_close() in /usr/local/apache/htdocs/PhoSigNet/include/locateconfig.inc.php:23 Stack trace: #0 /usr/local/apache/htdocs/PhoSigNet/proteintable.php(435): db_disconnect(Object(mysqli)) #1 {main} thrown in /usr/local/apache/htdocs/PhoSigNet/include/locateconfig.inc.php on line 23