| UniProt/SwissProt ID: | CCD40_HUMAN |
| Description: | coiled-coil domain containing 40 [Source:HGNC Symbol;Acc:26090] |
| Location: | chr17 q25.3 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| Y537 | GEIEAyKKSIM | PhosphoSitePlus | |
| S1028 | QRNVSsSLLEK | PhosphoSitePlus | |
| S1027 | TQRNVsSSLLE | PhosphoSitePlus | |
| S11 | GAAGRsHPEDG | PhosphoSitePlus | |
| S1029 | RNVSSsLLEKQ | PhosphoSitePlus | |
| S29 | EGNNEsHMVSP | PhosphoSitePlus | |
| T157 | RERRVtSPEPS | PhosphoSitePlus | |
| S151 | TGPPEsRERRV | PhosphoSitePlus | |
| S158 | ERRVTsPEPSH | PhosphoSitePlus | |
| Dephosphorylation site |
| CCD40_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000380679 | M920I | COSMIC | Ovarian Cancer | 21720365 | ENSP00000380679 | E783K | COSMIC | Skin Cancer | 21984974 | ENSP00000380679 | Q599K | COSMIC | Skin Cancer | 21984974 |
| Differential expressed protein |
| CCD40_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| CCD40_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| TNI3K_HUMAN | CCD40_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| KPCA_HUMAN | CCD40_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| Function Annotation |
| KEGG Pathway |
| CCD40_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0060287 | epithelial cilium movement involved in determinati | IEA | biological_process |
| GO:0005737 | cytoplasm | IEA | cellular_component |
| GO:0005929 | cilium | IEA | cellular_component |
| GO:0060286 | flagellar cell motility | IEA | biological_process |
| GO:0070286 | axonemal dynein complex assembly | IMP | biological_process |
| GO:0003674 | molecular_function | ND | molecular_function |
| GO:0060285 | ciliary cell motility | IEA | biological_process |