UniProt/SwissProt ID: | CC14A_HUMAN |
Description: | cell division cycle 14A [Source:HGNC Symbol;Acc:1718] |
Location: | chr1 p21.2 |
Node attribute: | phosphotase |
Phosphorylation site |
Position | PhosphoPeptide | Catalytic kinase | Source |
---|---|---|---|
S435 | QPFRLsSSLQG | PhosphoSitePlus | |
T444 | QGSAVtLKTSK | PhosphoSitePlus | |
S441 | SSLQGsAVTLK | PhosphoSitePlus | |
T222 | KKHNVtAVVRL | PhosphoSitePlus | |
S436 | PFRLSsSLQGS | PhosphoSitePlus | |
S583 | RFLSRsIPSLQ | PhosphoSitePlus | |
T447 | AVTLKtSKMAL | PhosphoSitePlus | |
S429 | HPRAVsQPFRL | PhosphoSitePlus | |
Dephosphorylation site |
CC14A_HUMAN do not have dephosphorylation site. |
Mutation site |
Ensembl ID | Variation | Source | Cancer name | Pubmed |
---|---|---|---|---|
ENSP00000336739 | D493Y | Sjoblom2006, COSMIC | Intestines Cancer | 16959974 |
ENSP00000336739 | D493Y | HPI | Colorectal Cancer | 16959974 |
Differential expressed protein |
CC14A_HUMAN is not differential expressed protein. |
Hyperphosphorylation site |
CC14A_HUMAN do not have hyperphosphorylation site. |
Direct Interaction Pair |
Source | Target | Relationship | Resource |
---|---|---|---|
CC14A_HUMAN | P53_HUMAN | phosphatase -> substrate | HPRD |
Function Annotation |
KEGG Pathway |
KEGG ID | Pathway |
---|---|
hsa04110 | Cell cycle |
Gene Ontology |
GO ID | GO_Term | Evidence | Ontology |
---|---|---|---|
GO:0004721 | phosphoprotein phosphatase activity | TAS | molecular_function |
GO:0016311 | dephosphorylation | IEA | biological_process |
GO:0005515 | protein binding | IPI | molecular_function |
GO:0004725 | protein tyrosine phosphatase activity | IEA | molecular_function |
GO:0051301 | cell division | IEA | biological_process |
GO:0005634 | nucleus | IDA | cellular_component |
GO:0006470 | protein dephosphorylation | IEA | biological_process |
GO:0007049 | cell cycle | IEA | biological_process |
GO:0005819 | spindle | IEA | cellular_component |
GO:0005737 | cytoplasm | IDA | cellular_component |
GO:0016791 | phosphatase activity | IEA | molecular_function |
GO:0008138 | protein tyrosine/serine/threonine phosphatase acti | IEA | molecular_function |
GO:0008283 | cell proliferation | TAS | biological_process |
GO:0005813 | centrosome | IDA | cellular_component |