Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:CBX1_HUMAN
Description:chromobox homolog 1 [Source:HGNC Symbol;Acc:1551]
Location:chr17 q21.32
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S91KADSDsEDKGEPhosphoSitePlus; HPRD
Y173LTWHSyPSEDDPhosphoSitePlus
S80HETDKsEGGKRPhosphoSitePlus
S89KRKADsDSEDKPhosphoSitePlus; HPRD; phosphoELM; SysPTM
T73LQSQKtAHETDPhosphoSitePlus
T77KTAHEtDKSEGPhosphoSitePlus
S70AEFLQsQKTAHChromoPhosphoSitePlus
S175WHSYPsEDDDKPhosphoSitePlus; HPRD
T51SDEDNtWEPEEChromoPhosphoSitePlus
S128IGATDsSGELMChromo_shadowPhosphoSitePlus
S172RLTWHsYPSEDChromo_shadowPhosphoSitePlus

Dephosphorylation site
CBX1_HUMAN do not have dephosphorylation site.

Mutation site
CBX1_HUMAN do not have mutation site.

Differential expressed protein
Ensembl IDCancer nameDesignSampleChangeRatioPubmed
ENSP00000377060Prostate CancerMetastasistissueUp3.418553995

Hyperphosphorylation site
CBX1_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
DYRK2_HUMANCBX1_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
CBX1_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0042802identical protein bindingIEAmolecular_function
GO:0000785chromatinIDAcellular_component
GO:0005654nucleoplasmTAScellular_component
GO:0010369chromocenterIEAcellular_component
GO:0045892negative regulation of transcription, DNA-dependenIEAbiological_process
GO:0005634nucleusIEAcellular_component
GO:0001940male pronucleusIEAcellular_component
GO:0005515protein bindingIEAmolecular_function
GO:0019899enzyme bindingIPImolecular_function
GO:0005721centromeric heterochromatinIEAcellular_component
GO:0000775chromosome, centromeric regionIDAcellular_component
GO:0000785chromatinIEAcellular_component
GO:0005720nuclear heterochromatinTAScellular_component
GO:0005515protein bindingIPImolecular_function
GO:0003682chromatin bindingTASmolecular_function
GO:0001939female pronucleusIEAcellular_component
GO:0005819spindleIDAcellular_component


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