| UniProt/SwissProt ID: | B3A3_HUMAN |
| Description: | solute carrier family 4, anion exchanger, member 3 [Source:HGNC Symbol;Acc:11029] |
| Location: | chr2 q35 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S13 | PPGGAsPLPQV | PhosphoSitePlus | |
| S580 | IATLMsDKLFH | HPRD | |
| S170 | KFSIGsDEDDS | PhosphoSitePlus; RegPhos | |
| T185 | GRAAVtKPLPS | PhosphoSitePlus | |
| S28 | EEPPLsPDVEE | PhosphoSitePlus; HPRD | |
| S67 | PSRSYsERDFE | PKCe | RegPhos |
| T982 | YTQKLtVPTGL | HPRD | |
| S67 | PSRSYsERDFE | PKCe(PKC epsilon | RegPhos |
| S961 | VPTGLsVTSPD | HPRD; RegPhos | |
| S988 | VPTGLsVTSPD | HPRD | |
| S67 | PSRSYsERDFE | PRKCE | HPRD |
| T958 | KLTVPtGLSVT | HPRD; RegPhos | |
| T985 | KLTVPtGLSVT | HPRD | |
| S67 | PSRSYsERDFE | PKC_epsilon | phosphoELM |
| T291 | KKPSRtQGGRG | PhosphoSitePlus | |
| S198 | PHTDKsPQHSS | RegPhos | |
| S607 | IATLMsDKLFH | HPRD | |
| S580 | IATLMsDKLFH | Band_3_cyto | PhosphoSitePlus |
| S297 | QGGRGsPSGLA | PhosphoSitePlus; RegPhos | |
| S969 | SPDKRsWFIPP | HCO3_cotransp | PhosphoSitePlus |
| T955 | YTQKLtVPTGL | HPRD; RegPhos | |
| Dephosphorylation site |
| B3A3_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000273063 | I1140M | COSMIC | Head and Neck Cancer | 21798897 | ENSP00000273063 | R370H | COSMIC | Ovarian Cancer | 21720365 | ENSP00000350756 | L1131V | BIOMART | Pancreatic Cancer | 21930507, 21930502 | ENSP00000314006 | L1131V | BIOMART | Pancreatic Cancer | 21930507, 21930502 | ENSP00000350756 | R343H | TCGA | Ovarian Cancer | 21720365, 18772890 | ENSP00000362865 | R343H | TCGA | Ovarian Cancer | 21720365, 18772890 | ENSP00000314006 | R343H | TCGA | Ovarian Cancer | 21720365, 18772890 | ENSP00000273063 | D457N | COSMIC | Skin Cancer | 21984974 | ENSP00000273063 | G327R | COSMIC | Head and Neck Cancer | 21798893 | ENSP00000273063 | L1158V | BIOMART | Pancreatic Cancer | 21930507, 21930502 | ENSP00000362865 | L1131V | BIOMART | Pancreatic Cancer | 21930507, 21930502 | ENSP00000362867 | L1158V | BIOMART | Pancreatic Cancer | 21930507, 21930502 | ENSP00000273063 | G1062V | COSMIC | Ovarian Cancer | 20826764 |
| Differential expressed protein |
| B3A3_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| B3A3_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| KPCE_HUMAN | B3A3_HUMAN | kinase -> substrate | HPRD |
| ZAGL2_HUMAN | B3A3_HUMAN | kinase -> substrate | RegPhos |
| Function Annotation |
| KEGG Pathway |
| B3A3_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0005886 | plasma membrane | TAS | cellular_component |
| GO:0005452 | inorganic anion exchanger activity | IEA | molecular_function |
| GO:0015701 | bicarbonate transport | TAS | biological_process |
| GO:0005886 | plasma membrane | IEA | cellular_component |
| GO:0051453 | regulation of intracellular pH | IEA | biological_process |
| GO:0006811 | ion transport | TAS | biological_process |
| GO:0005887 | integral to plasma membrane | TAS | cellular_component |
| GO:0016020 | membrane | TAS | cellular_component |
| GO:0055085 | transmembrane transport | TAS | biological_process |
| GO:0006810 | transport | TAS | biological_process |
| GO:0016021 | integral to membrane | IEA | cellular_component |
| GO:0008509 | anion transmembrane transporter activity | IEA | molecular_function |
| GO:0006820 | anion transport | IEA | biological_process |
| GO:0015301 | anion:anion antiporter activity | IEA | molecular_function |
| GO:0005215 | transporter activity | IEA | molecular_function |