| UniProt/SwissProt ID: | ATRIP_HUMAN |
| Description: | ATR interacting protein [Source:HGNC Symbol;Acc:33499] |
| Location: | chr3 p21.31 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| T307 | RQRSNtQGSIL | HPRD | |
| S518 | LVHRLsDGDMT | PhosphoSitePlus; HPRD; phosphoELM; RegPhos | |
| S221 | AAPSVsHVSPR | PhosphoSitePlus; HPRD | |
| S72 | ASQALsQCPAA | IncA | PhosphoSitePlus |
| S68 | LDTLAsQALSQ | ATR | HPRD; phosphoELM; RegPhos |
| T523 | SDGDMtSALRG | PhosphoSitePlus; HPRD | |
| S72 | ASQALsQCPAA | ATR | HPRD; phosphoELM; RegPhos |
| S239 | KPEACsPQFGK | CDK2 | phosphoELM |
| S305 | SWRQRsNTQGS | HPRD | |
| S239 | KPEACsPQFGK | PhosphoSitePlus | |
| S68 | LDTLAsQALSQ | PhosphoSitePlus | |
| S310 | SNTQGsILINL | HPRD | |
| S224 | SVSHVsPRKNP | PhosphoSitePlus; HPRD; phosphoELM | |
| S224 | SVSHVsPRKNP | CDK2 | phosphoELM |
| Y636 | LLLLLyMYITS | PhosphoSitePlus | |
| S38 | RARGFsAAAAP | PhosphoSitePlus | |
| Dephosphorylation site |
| ATRIP_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000323099 | H418R | COSMIC | Ovarian Cancer | 21720365 |
| Differential expressed protein |
| ATRIP_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| ATRIP_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| ZAGL2_HUMAN | ATRIP_HUMAN | kinase -> substrate | RegPhos |
| ATR_HUMAN | ATRIP_HUMAN | kinase -> substrate | RegPhos |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa03460 | Fanconi anemia pathway |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0000075 | cell cycle checkpoint | TAS | biological_process |
| GO:0005515 | protein binding | IEA | molecular_function |
| GO:0006281 | DNA repair | IEA | biological_process |
| GO:0005654 | nucleoplasm | TAS | cellular_component |
| GO:0005515 | protein binding | IPI | molecular_function |
| GO:0006260 | DNA replication | TAS | biological_process |
| GO:0000077 | DNA damage checkpoint | TAS | biological_process |