Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:ASCC3_HUMAN
Description:activating signal cointegrator 1 complex subunit 3 [Source:HGNC Symbol;Acc:18697]
Location:chr6 q16.3
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S2195TKVSDsLTDLAPhosphoSitePlus; HPRD
T592KWDVVtRKSVGDEADPhosphoSitePlus
T1915DTDTKtVLDQAHPRD
S1746GGTITsKQDALPhosphoSitePlus
S1490RIVGLsTALANDEADPhosphoSitePlus
S595VVTRKsVGDVAHPRD
S640VESTQsMIRILDEADPhosphoSitePlus
T1915DTDTKtVLDQASec63PhosphoSitePlus
T1480FISSHtEKPVRDEADPhosphoSitePlus
T973RFEERtGYFSSPhosphoSitePlus
S1553AIRSHsPAKPVPhosphoSitePlus; HPRD
Y1909LPCPDyDTDTKSec63PhosphoSitePlus
Y975EERTGyFSSTDPhosphoSitePlus
T209LQEACtPELKPPhosphoSitePlus
S170KNLAFsFDMHDPhosphoSitePlus
T584QMLVTtPEKWDDEADPhosphoSitePlus
S1551FQAIRsHSPAKPhosphoSitePlus; HPRD
S637LRQVEsTQSMIDEADPhosphoSitePlus
S1131PLRQFsILPPHSec63PhosphoSitePlus
S1563VLIFVsSRRQTPhosphoSitePlus; HPRD
T578SEILRtQMLVTDEADPhosphoSitePlus
T1745AGGTItSKQDAPhosphoSitePlus
T565IVKELtGDMQLHPRD

Dephosphorylation site
ASCC3_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000358159L1110QBIOMARTBreast Cancer21930507, 21930502

Differential expressed protein
ASCC3_HUMAN is not differential expressed protein.

Hyperphosphorylation site
ASCC3_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
TGFR2_HUMANASCC3_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
ASCC3_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0003676nucleic acid bindingIEAmolecular_function
GO:0006355regulation of transcription, DNA-dependentIEAbiological_process
GO:0032508DNA duplex unwindingIDAbiological_process
GO:0005737cytoplasmIDAcellular_component
GO:0005515protein bindingIPImolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0017111nucleoside-triphosphatase activityIEAmolecular_function
GO:0043140ATP-dependent 3'-5' DNA helicase activityIDAmolecular_function
GO:0008026ATP-dependent helicase activityIEAmolecular_function
GO:0006351transcription, DNA-dependentIEAbiological_process
GO:0006307DNA dealkylation involved in DNA repairIDAbiological_process
GO:0000166nucleotide bindingIEAmolecular_function
GO:0005737cytoplasmIEAcellular_component
GO:0004386helicase activityIEAmolecular_function
GO:0005794Golgi apparatusIDAcellular_component
GO:0005634nucleusTAScellular_component
GO:0003677DNA bindingIEAmolecular_function
GO:0005622intracellularIDAcellular_component
GO:0008283cell proliferationIMPbiological_process
GO:0016787hydrolase activityIEAmolecular_function


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