Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:AP2B_HUMAN
Description:transcription factor AP-2 beta (activating enhancer binding protein 2 beta) [Source:HGNC Symbol;Acc:11743]
Location:chr6 p12.3
Node attribute:TF

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S258VQRRLsPPECLTF_AP-2PhosphoSitePlus
S223FLGGMsVNTGEHPRD
Y246SSTSKyKVTVGHPRD
S244LLSSTsKYKVTTF_AP-2PhosphoSitePlus
Y26KYEDIyEDRHDPhosphoSitePlus
S258VQRRLsPPECLphosphoELM
S120GSEAGsLLPQPPhosphoSitePlus

Dephosphorylation site
AP2B_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000377265S45LCOSMICHead and Neck Cancer21798893

Differential expressed protein
AP2B_HUMAN is not differential expressed protein.

Hyperphosphorylation site
AP2B_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
AP2B_HUMANSODM_HUMANTF -> target geneTRANSFAC

Function Annotation
KEGG Pathway
AP2B_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0043525positive regulation of neuron apoptotic processIDAbiological_process
GO:0010960magnesium ion homeostasisIEAbiological_process
GO:0055075potassium ion homeostasisIEAbiological_process
GO:0000979RNA polymerase II core promoter sequence-specific IEAmolecular_function
GO:0035909aorta morphogenesisIEAbiological_process
GO:0001106RNA polymerase II transcription corepressor activiIEAmolecular_function
GO:0001822kidney developmentIEAbiological_process
GO:0035137hindlimb morphogenesisISSbiological_process
GO:0006006glucose metabolic processIMPbiological_process
GO:0097276cellular creatinine homeostasisIEAbiological_process
GO:0001105RNA polymerase II transcription coactivator activiISSmolecular_function
GO:0045444fat cell differentiationIEPbiological_process
GO:0042803protein homodimerization activityIPImolecular_function
GO:0000979RNA polymerase II core promoter sequence-specific IDAmolecular_function
GO:0072017distal tubule developmentIEAbiological_process
GO:0005515protein bindingIEAmolecular_function
GO:0003713transcription coactivator activityIDAmolecular_function
GO:0010960magnesium ion homeostasisISSbiological_process
GO:0042593glucose homeostasisISSbiological_process
GO:0043027cysteine-type endopeptidase inhibitor activity invISSmolecular_function
GO:0055062phosphate ion homeostasisISSbiological_process
GO:0000122negative regulation of transcription from RNA polyIEAbiological_process
GO:0043588skin developmentIEAbiological_process
GO:0001105RNA polymerase II transcription coactivator activiIEAmolecular_function
GO:0035136forelimb morphogenesisIEAbiological_process
GO:0010842retina layer formationIEPbiological_process
GO:0043066negative regulation of apoptotic processIEAbiological_process
GO:0030510regulation of BMP signaling pathwayISSbiological_process
GO:0030510regulation of BMP signaling pathwayIEAbiological_process
GO:0055078sodium ion homeostasisISSbiological_process
GO:0055075potassium ion homeostasisISSbiological_process
GO:0008284positive regulation of cell proliferationIEAbiological_process
GO:0003700sequence-specific DNA binding transcription factorIDAmolecular_function
GO:0043154negative regulation of cysteine-type endopeptidaseISSbiological_process
GO:0045944positive regulation of transcription from RNA polyIEAbiological_process
GO:0003714transcription corepressor activityIDAmolecular_function
GO:0035137hindlimb morphogenesisIEAbiological_process
GO:0097277cellular urea homeostasisIEAbiological_process
GO:0072017distal tubule developmentISSbiological_process
GO:0097070ductus arteriosus closureIEAbiological_process
GO:0003091renal water homeostasisIEAbiological_process
GO:0001158enhancer sequence-specific DNA bindingIDAmolecular_function
GO:0050796regulation of insulin secretionIMPbiological_process
GO:0000983RNA polymerase II core promoter sequence-specific ISSmolecular_function
GO:0072044collecting duct developmentIEAbiological_process
GO:0001106RNA polymerase II transcription corepressor activiISSmolecular_function
GO:0046982protein heterodimerization activityIPImolecular_function
GO:0097275cellular ammonia homeostasisIEAbiological_process
GO:0035909aorta morphogenesisISSbiological_process
GO:0006355regulation of transcription, DNA-dependentIDAbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0003091renal water homeostasisISSbiological_process
GO:0007423sensory organ developmentIEAbiological_process
GO:0043027cysteine-type endopeptidase inhibitor activity invIEAmolecular_function
GO:0043154negative regulation of cysteine-type endopeptidaseIEAbiological_process
GO:0001822kidney developmentISSbiological_process
GO:0045892negative regulation of transcription, DNA-dependenIDAbiological_process
GO:0042593glucose homeostasisIEAbiological_process
GO:0045944positive regulation of transcription from RNA polyIDAbiological_process
GO:0055074calcium ion homeostasisIEAbiological_process
GO:0048485sympathetic nervous system developmentISSbiological_process
GO:0072044collecting duct developmentISSbiological_process
GO:0046983protein dimerization activityIDAmolecular_function
GO:0001077RNA polymerase II core promoter proximal region seIEAmolecular_function
GO:0000122negative regulation of transcription from RNA polyIDAbiological_process
GO:0048485sympathetic nervous system developmentIEAbiological_process
GO:0043565sequence-specific DNA bindingIDAmolecular_function
GO:0006366transcription from RNA polymerase II promoterIEAbiological_process
GO:0035136forelimb morphogenesisISSbiological_process
GO:0005634nucleusICcellular_component
GO:0055074calcium ion homeostasisISSbiological_process
GO:0008284positive regulation of cell proliferationIDAbiological_process
GO:0055062phosphate ion homeostasisIEAbiological_process
GO:0000981sequence-specific DNA binding RNA polymerase II trIDAmolecular_function
GO:0008285negative regulation of cell proliferationIDAbiological_process
GO:0045595regulation of cell differentiationIDAbiological_process
GO:0045444fat cell differentiationIEAbiological_process
GO:0055078sodium ion homeostasisIEAbiological_process
GO:0035810positive regulation of urine volumeIEAbiological_process
GO:0072210metanephric nephron developmentIEAbiological_process
GO:0003677DNA bindingTASmolecular_function
GO:0035810positive regulation of urine volumeISSbiological_process
GO:0045893positive regulation of transcription, DNA-dependenIDAbiological_process
GO:0097275cellular ammonia homeostasisISSbiological_process
GO:0097277cellular urea homeostasisISSbiological_process
GO:0000983RNA polymerase II core promoter sequence-specific IEAmolecular_function
GO:0097276cellular creatinine homeostasisISSbiological_process
GO:0097070ductus arteriosus closureISSbiological_process
GO:0003713transcription coactivator activityIEAmolecular_function
GO:0043066negative regulation of apoptotic processISSbiological_process