Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:ANPRC_HUMAN
Description:natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C) [Source:HGNC Symbol;Acc:7945]
Location:chr5 p13.3
Node attribute:receptor

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S533ELREDsIRSHFPhosphoSitePlus; phosphoELM; SysPTM
Y316EAKQAySSLQTANF_receptorPhosphoSitePlus
S532ELREDsIRSHFHPRD
S148VARLAsHWDLPANF_receptorPhosphoSitePlus
S156DLPMLsAGALAANF_receptorPhosphoSitePlus

Dephosphorylation site
ANPRC_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000398028L492FTCGAOvarian Cancer21720365, 18772890
ENSP00000398028L491FTCGAOvarian Cancer21720365, 18772890

Differential expressed protein
ANPRC_HUMAN is not differential expressed protein.

Hyperphosphorylation site
ANPRC_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
ANFB_HUMANANPRC_HUMANligand -> receptorHPMR
ANF_HUMANANPRC_HUMANligand -> receptorHPMR

Function Annotation
KEGG Pathway
ANPRC_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0002158osteoclast proliferationIEAbiological_process
GO:0042803protein homodimerization activityIEAmolecular_function
GO:0008217regulation of blood pressureISSbiological_process
GO:0033688regulation of osteoblast proliferationISSbiological_process
GO:0035810positive regulation of urine volumeIEAbiological_process
GO:0008528G-protein coupled peptide receptor activityISSmolecular_function
GO:0033688regulation of osteoblast proliferationIEAbiological_process
GO:0017046peptide hormone bindingISSmolecular_function
GO:0016020membraneIEAcellular_component
GO:0007194negative regulation of adenylate cyclase activityIEAbiological_process
GO:0035810positive regulation of urine volumeISSbiological_process
GO:0007193adenylate cyclase-inhibiting G-protein coupled recIEAbiological_process
GO:0008217regulation of blood pressureIEAbiological_process
GO:0002158osteoclast proliferationISSbiological_process
GO:0005887integral to plasma membraneICcellular_component
GO:0051000positive regulation of nitric-oxide synthase activIEAbiological_process
GO:0017046peptide hormone bindingIEAmolecular_function
GO:0008528G-protein coupled peptide receptor activityIEAmolecular_function
GO:0001501skeletal system developmentIEAbiological_process
GO:0016941natriuretic peptide receptor activityIDAmolecular_function
GO:0051000positive regulation of nitric-oxide synthase activISSbiological_process
GO:0001501skeletal system developmentISSbiological_process
GO:0007200phospholipase C-activating G-protein coupled recepIEAbiological_process
GO:0042562hormone bindingIPImolecular_function


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