Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:ANGP2_HUMAN
Description:angiopoietin 2 [Source:HGNC Symbol;Acc:485]
Location:chr8 p23.1
Node attribute:ligand

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y482WKGSGySLKATFibrinogen_CPhosphoSitePlus

Dephosphorylation site
ANGP2_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000314897L406HCOSMICHead and Neck Cancer21798897
ENSP00000400782R155KBIOMARTBreast Cancer21930507, 21930502
ENSP00000314897R155KBIOMARTBreast Cancer21930507, 21930502
ENSP00000314897E358QCOSMICSkin Cancer21984974

Differential expressed protein
ANGP2_HUMAN is not differential expressed protein.

Hyperphosphorylation site
ANGP2_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
ANGP2_HUMANTIE2_HUMANligand -> receptorHPMR

Function Annotation
KEGG Pathway
ANGP2_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0042995cell projectionIEAcellular_component
GO:0016525negative regulation of angiogenesisIEAbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0009314response to radiationIEAbiological_process
GO:0031100organ regenerationIEAbiological_process
GO:0043537negative regulation of blood vessel endothelial ceIDAbiological_process
GO:0001666response to hypoxiaIEAbiological_process
GO:0007596blood coagulationTASbiological_process
GO:0045766positive regulation of angiogenesisIEAbiological_process
GO:0005576extracellular regionTAScellular_component
GO:0071363cellular response to growth factor stimulusIEAbiological_process
GO:0009612response to mechanical stimulusIEAbiological_process
GO:0072012glomerulus vasculature developmentIEAbiological_process
GO:0005634nucleusIEAcellular_component
GO:0009749response to glucose stimulusIEAbiological_process
GO:0060135maternal process involved in female pregnancyIEAbiological_process
GO:0050900leukocyte migrationTASbiological_process
GO:0072012glomerulus vasculature developmentISSbiological_process
GO:0014070response to organic cyclic compoundIEAbiological_process
GO:0048014Tie receptor signaling pathwayIDAbiological_process
GO:0005615extracellular spaceIEAcellular_component
GO:0048514blood vessel morphogenesisIEAbiological_process
GO:0007165signal transductionTASbiological_process
GO:0014823response to activityIEAbiological_process
GO:0030971receptor tyrosine kinase bindingIPImolecular_function
GO:0007281germ cell developmentIEAbiological_process
GO:0046872metal ion bindingIEAmolecular_function
GO:0005615extracellular spaceIDAcellular_component
GO:0010812negative regulation of cell-substrate adhesionIEAbiological_process
GO:0005886plasma membraneIEAcellular_component
GO:0005515protein bindingIEAmolecular_function
GO:0050928negative regulation of positive chemotaxisIDAbiological_process
GO:0001525angiogenesisIEAbiological_process
GO:0005102receptor bindingTASmolecular_function