Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:ANGP1_HUMAN
Description:angiopoietin 1 [Source:HGNC Symbol;Acc:484]
Location:chr8 q23.1
Node attribute:ligand

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
T409YLKGHtGTAGKFibrinogen_CPhosphoSitePlus
Y386EGNRAySQYDRFibrinogen_CPhosphoSitePlus
Y401NEKQNyRLYLKFibrinogen_CPhosphoSitePlus
T325NGGGWtVIQHRFibrinogen_CPhosphoSitePlus
T411KGHTGtAGKQSFibrinogen_CPhosphoSitePlus
S6MTVFLsFAFLAPhosphoSitePlus
Y404QNYRLyLKGHTFibrinogen_CPhosphoSitePlus
T2____MtVFLSFPhosphoSitePlus
Y389RAYSQyDRFHIFibrinogen_CPhosphoSitePlus
Y303GIYTIyINNMPFibrinogen_CPhosphoSitePlus
S297AGFNKsGIYTIFibrinogen_CPhosphoSitePlus
Y300NKSGIyTIYINFibrinogen_CPhosphoSitePlus

Dephosphorylation site
ANGP1_HUMAN do not have dephosphorylation site.

Mutation site
ANGP1_HUMAN do not have mutation site.

Differential expressed protein
ANGP1_HUMAN is not differential expressed protein.

Hyperphosphorylation site
ANGP1_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
ANGP1_HUMANTIE2_HUMANligand -> receptorHPMR
ANGP1_HUMANTIE1_HUMANligand -> receptorHPMR

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa05323Rheumatoid arthritis

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0043116negative regulation of vascular permeabilityIEAbiological_process
GO:0030971receptor tyrosine kinase bindingIPImolecular_function
GO:0005902microvillusIDAcellular_component
GO:0050731positive regulation of peptidyl-tyrosine phosphoryIEAbiological_process
GO:2000352negative regulation of endothelial cell apoptotic IDAbiological_process
GO:0033138positive regulation of peptidyl-serine phosphorylaIEAbiological_process
GO:0070374positive regulation of ERK1 and ERK2 cascadeIDAbiological_process
GO:0007171activation of transmembrane receptor protein tyrosIDAbiological_process
GO:0001701in utero embryonic developmentIEAbiological_process
GO:0030210heparin biosynthetic processIDAbiological_process
GO:0031589cell-substrate adhesionIEAbiological_process
GO:0048014Tie receptor signaling pathwayIDAbiological_process
GO:0043066negative regulation of apoptotic processIEAbiological_process
GO:0007169transmembrane receptor protein tyrosine kinase sigIEAbiological_process
GO:0010595positive regulation of endothelial cell migrationIDAbiological_process
GO:0001525angiogenesisIEAbiological_process
GO:0007596blood coagulationTASbiological_process
GO:0050918positive chemotaxisIDAbiological_process
GO:0043536positive regulation of blood vessel endothelial ceIDAbiological_process
GO:0014842regulation of satellite cell proliferationIDAbiological_process
GO:0050900leukocyte migrationTASbiological_process
GO:0005886plasma membraneIDAcellular_component
GO:0072012glomerulus vasculature developmentIEAbiological_process
GO:0034394protein localization to cell surfaceIDAbiological_process
GO:0030154cell differentiationIEAbiological_process
GO:0002092positive regulation of receptor internalizationIDAbiological_process
GO:0014068positive regulation of phosphatidylinositol 3-kinaIEAbiological_process
GO:0005102receptor bindingIEAmolecular_function
GO:0030097hemopoiesisIEAbiological_process
GO:0005615extracellular spaceIEAcellular_component
GO:0045785positive regulation of cell adhesionIEAbiological_process
GO:0005576extracellular regionTAScellular_component
GO:0002040sprouting angiogenesisIDAbiological_process
GO:0007162negative regulation of cell adhesionIDAbiological_process
GO:0031398positive regulation of protein ubiquitinationIDAbiological_process
GO:0045121membrane raftIDAcellular_component
GO:0007165signal transductionIEAbiological_process
GO:0051897positive regulation of protein kinase B signaling IDAbiological_process


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