Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:ANFB_HUMAN
Description:natriuretic peptide B [Source:HGNC Symbol;Acc:7940]
Location:chr1 p36.22
Node attribute:ligand

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S103LRAPRsPKMVQANPPhosphoSitePlus
T84SREVAtEGIRGANPPhosphoSitePlus

Dephosphorylation site
ANFB_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000365651E60*COSMICOvarian Cancer21720365
ENSP00000365651R99WCOSMICOvarian Cancer21720365

Differential expressed protein
ANFB_HUMAN is not differential expressed protein.

Hyperphosphorylation site
ANFB_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
ANFB_HUMANANPRC_HUMANligand -> receptorHPMR
ANFB_HUMANANPRB_HUMANligand -> receptorHPMR

Function Annotation
KEGG Pathway
ANFB_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0043434response to peptide hormone stimulusIEAbiological_process
GO:0008613diuretic hormone activityTASmolecular_function
GO:0030308negative regulation of cell growthIEAbiological_process
GO:0007168receptor guanylyl cyclase signaling pathwayIDAbiological_process
GO:0050880regulation of blood vessel sizeIEAbiological_process
GO:0001666response to hypoxiaIEAbiological_process
GO:0016525negative regulation of angiogenesisTASbiological_process
GO:0008217regulation of blood pressureNASbiological_process
GO:0007507heart developmentIEAbiological_process
GO:0048471perinuclear region of cytoplasmIEAcellular_component
GO:0007166cell surface receptor signaling pathwayNASbiological_process
GO:0008217regulation of blood pressureIEAbiological_process
GO:0005576extracellular regionTAScellular_component
GO:0005179hormone activityNASmolecular_function
GO:0071260cellular response to mechanical stimulusIEAbiological_process
GO:0035810positive regulation of urine volumeTASbiological_process
GO:0051592response to calcium ionIEAbiological_process
GO:0005737cytoplasmIEAcellular_component
GO:0051428peptide hormone receptor bindingIEAmolecular_function
GO:0005102receptor bindingIPImolecular_function
GO:0032496response to lipopolysaccharideIEAbiological_process
GO:0048662negative regulation of smooth muscle cell proliferIEAbiological_process
GO:0006954inflammatory responseIEAbiological_process
GO:0014070response to organic cyclic compoundIEAbiological_process
GO:0005179hormone activityIEAmolecular_function
GO:0005615extracellular spaceIEAcellular_component
GO:0005615extracellular spaceNAScellular_component
GO:0006182cGMP biosynthetic processIDAbiological_process
GO:0030308negative regulation of cell growthNASbiological_process
GO:0042312regulation of vasodilationNASbiological_process
GO:0006182cGMP biosynthetic processIEAbiological_process
GO:0042493response to drugIEAbiological_process
GO:0007589body fluid secretionTASbiological_process
GO:0035815positive regulation of renal sodium excretionTASbiological_process
GO:0005634nucleusIEAcellular_component
GO:0043114regulation of vascular permeabilityTASbiological_process