Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:AMRP_HUMAN
Description:low density lipoprotein receptor-related protein associated protein 1 [Source:HGNC Symbol;Acc:6701]
Location:chr4 p16.3
Node attribute:ligand

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
T248HQGYStEAEFEAlpha-2-MRAP_CPhosphoSitePlus
S137QVTSNsLSGTQPhosphoSitePlus
Y336TKELGyTVKKHAlpha-2-MRAP_CPhosphoSitePlus
S45NQPKPsPKRESHPRD
S230KEKLRsINQGLHPRD
S247SHQGYsTEAEFAlpha-2-MRAP_CPhosphoSitePlus
S135ARQVTsNSLSGPhosphoSitePlus
T141NSLSGtQEDGLPhosphoSitePlus
S230KEKLRsINQGLAlpha-2-MRAP_CPhosphoSitePlus
S45NQPKPsPKRESAlpha-2-MRAP_NPhosphoSitePlus
T248HQGYStEAEFEHPRD
S247SHQGYsTEAEFHPRD

Dephosphorylation site
AMRP_HUMAN do not have dephosphorylation site.

Mutation site
AMRP_HUMAN do not have mutation site.

Differential expressed protein
Ensembl IDCancer nameDesignSampleChangeRatioPubmed
ENSP00000421922hepatitis C virusNormal vs. CancertissueDown0.318715028
ENSP00000421922Ovarian CancerTreatment (Paclitaxel-sensitive vs. Paclitaxel-resistant)cell lineUp1.319951750

Hyperphosphorylation site
AMRP_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
AMRP_HUMANLRP1_HUMANligand -> receptorHPMR

Function Annotation
KEGG Pathway
AMRP_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0050750low-density lipoprotein particle receptor bindingIEAmolecular_function
GO:0032091negative regulation of protein bindingIDAbiological_process
GO:0048237rough endoplasmic reticulum lumenIEAcellular_component
GO:0050750low-density lipoprotein particle receptor bindingIDAmolecular_function
GO:0070326very-low-density lipoprotein particle receptor binIPImolecular_function
GO:0048019receptor antagonist activityIDAmolecular_function
GO:0004873asialoglycoprotein receptor activityTASmolecular_function
GO:0051082unfolded protein bindingTASmolecular_function
GO:0005576extracellular regionIDAcellular_component
GO:0031982vesicleIEAcellular_component
GO:0035473lipase bindingIEAmolecular_function
GO:1900116extracellular negative regulation of signal transdIDAbiological_process
GO:0006457protein foldingTASbiological_process
GO:0008201heparin bindingIEAmolecular_function
GO:0016192vesicle-mediated transportTASbiological_process
GO:0005886plasma membraneIDAcellular_component
GO:0016021integral to membraneTAScellular_component
GO:0009986cell surfaceIEAcellular_component
GO:0005783endoplasmic reticulumIDAcellular_component
GO:0010916negative regulation of very-low-density lipoproteiIDAbiological_process
GO:1900222negative regulation of beta-amyloid clearanceIGIbiological_process


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