Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:AMHR2_HUMAN
Description:anti-Mullerian hormone receptor, type II [Source:HGNC Symbol;Acc:465]
Location:chr12 q13.13
Node attribute:PPI(target); receptor; gene

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S189EPRPDsGRDWSPhosphoSitePlus

Dephosphorylation site
AMHR2_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000257863D333NBIOMARTBreast Cancer21930507, 21930502
ENSP00000257863E380KBIOMARTBreast Cancer21930507, 21930502
ENSP00000257863R407*BIOMARTBrain Cancer21930507, 21930502

Differential expressed protein
AMHR2_HUMAN is not differential expressed protein.

Hyperphosphorylation site
AMHR2_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
MIS_HUMANAMHR2_HUMANligand -> receptorHPMR
GDF7_HUMANAMHR2_HUMANotherKEGG
ITF2_HUMANAMHR2_HUMANTF -> target geneTRANSFAC
STF1_HUMANAMHR2_HUMANTF -> target geneTRANSFAC

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04350TGF-beta signaling pathway
hsa04060Cytokine-cytokine receptor interaction

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0007548sex differentiationISSbiological_process
GO:0004713protein tyrosine kinase activityIEAmolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0046872metal ion bindingIEAmolecular_function
GO:0007548sex differentiationIEAbiological_process
GO:0016020membraneIEAcellular_component
GO:0005024transforming growth factor beta-activated receptorIEAmolecular_function
GO:0004672protein kinase activityIEAmolecular_function
GO:0005026transforming growth factor beta receptor activity,IEAmolecular_function
GO:0005515protein bindingIPImolecular_function
GO:0005887integral to plasma membraneIEAcellular_component
GO:0007179transforming growth factor beta receptor signalingIEAbiological_process
GO:0001880Mullerian duct regressionNASbiological_process
GO:0016772transferase activity, transferring phosphorus-contIEAmolecular_function
GO:0042562hormone bindingIPImolecular_function
GO:0006468protein phosphorylationIEAbiological_process
GO:0007165signal transductionIMPbiological_process
GO:0004675transmembrane receptor protein serine/threonine kiIEAmolecular_function
GO:0004872receptor activityIMPmolecular_function


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