Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:ADIPO_HUMAN
Description:adiponectin, C1Q and collagen domain containing [Source:HGNC Symbol;Acc:13633]
Location:chr3 q27.3
Node attribute:ligand; PPI(source)

Phosphorylation site
ADIPO_HUMAN do not have phosphorylation site.

Dephosphorylation site
ADIPO_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000389814G148VTCGAOvarian Cancer21720365, 18772890
ENSP00000320709G148VTCGAOvarian Cancer21720365, 18772890
ENSP00000405611G148VTCGAOvarian Cancer21720365, 18772890
ENSP00000389814A41VBIOMARTBreast Cancer21930507, 21930502
ENSP00000320709G148VCOSMICOvarian Cancer21720365
ENSP00000320709A41VBIOMARTBreast Cancer21930507, 21930502
ENSP00000405611A41VBIOMARTBreast Cancer21930507, 21930502

Differential expressed protein
ADIPO_HUMAN is not differential expressed protein.

Hyperphosphorylation site
ADIPO_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
ADIPO_HUMANADR2_HUMANligand -> receptorHPMR
ADIPO_HUMANADR1_HUMANligand -> receptorHPMR
ADIPO_HUMANADR1_HUMANotherKEGG

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04920Adipocytokine signaling pathway
hsa04930Type II diabetes mellitus
hsa03320PPAR signaling pathway

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0030336negative regulation of cell migrationISSbiological_process
GO:0046888negative regulation of hormone secretionIEAbiological_process
GO:0045599negative regulation of fat cell differentiationIDAbiological_process
GO:0043407negative regulation of MAP kinase activityIEAbiological_process
GO:2000279negative regulation of DNA biosynthetic processIDAbiological_process
GO:0051384response to glucocorticoid stimulusIEAbiological_process
GO:0010906regulation of glucose metabolic processIDAbiological_process
GO:0019395fatty acid oxidationISSbiological_process
GO:0001934positive regulation of protein phosphorylationIDAbiological_process
GO:0006091generation of precursor metabolites and energyTASbiological_process
GO:2000590negative regulation of metanephric mesenchymal celISSbiological_process
GO:0045721negative regulation of gluconeogenesisIEAbiological_process
GO:2000590negative regulation of metanephric mesenchymal celIEAbiological_process
GO:0014912negative regulation of smooth muscle cell migratioIDAbiological_process
GO:0071639positive regulation of monocyte chemotactic proteiIDAbiological_process
GO:2000467positive regulation of glycogen (starch) synthase IEAbiological_process
GO:0043123positive regulation of I-kappaB kinase/NF-kappaB cISSbiological_process
GO:0045923positive regulation of fatty acid metabolic procesISSbiological_process
GO:0071320cellular response to cAMPIEAbiological_process
GO:0045599negative regulation of fat cell differentiationIEAbiological_process
GO:0030336negative regulation of cell migrationIEAbiological_process
GO:0060081membrane hyperpolarizationIEAbiological_process
GO:0010745negative regulation of macrophage derived foam celIDAbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0072659protein localization to plasma membraneIDAbiological_process
GO:0043407negative regulation of MAP kinase activityISSbiological_process
GO:0005102receptor bindingIEAmolecular_function
GO:2000478positive regulation of metanephric glomerular viscISSbiological_process
GO:0043124negative regulation of I-kappaB kinase/NF-kappaB cIDAbiological_process
GO:0010875positive regulation of cholesterol effluxIDAbiological_process
GO:0050805negative regulation of synaptic transmissionIDAbiological_process
GO:0033034positive regulation of myeloid cell apoptotic procIDAbiological_process
GO:0005581collagenIEAcellular_component
GO:0032757positive regulation of interleukin-8 productionIDAbiological_process
GO:0042803protein homodimerization activityIPImolecular_function
GO:0010642negative regulation of platelet-derived growth facIDAbiological_process
GO:0070373negative regulation of ERK1 and ERK2 cascadeIDAbiological_process
GO:0035690cellular response to drugIEAbiological_process
GO:0032270positive regulation of cellular protein metabolic IDAbiological_process
GO:0035690cellular response to drugISSbiological_process
GO:2000584negative regulation of platelet-derived growth facIEAbiological_process
GO:0010739positive regulation of protein kinase A signaling IDAbiological_process
GO:2000478positive regulation of metanephric glomerular viscIEAbiological_process
GO:0005615extracellular spaceIDAcellular_component
GO:0007623circadian rhythmIEAbiological_process
GO:0050873brown fat cell differentiationIEAbiological_process
GO:0042493response to drugIEAbiological_process
GO:0045892negative regulation of transcription, DNA-dependenIEAbiological_process
GO:0090317negative regulation of intracellular protein transIDAbiological_process
GO:0051260protein homooligomerizationIEAbiological_process
GO:0032720negative regulation of tumor necrosis factor produIDAbiological_process
GO:2000461negative regulation of eukaryotic cell surface binIDAbiological_process
GO:0070994detection of oxidative stressIEAbiological_process
GO:0045715negative regulation of low-density lipoprotein parIDAbiological_process
GO:0051899membrane depolarizationIEAbiological_process
GO:2000481positive regulation of cAMP-dependent protein kinaIEAbiological_process
GO:0045650negative regulation of macrophage differentiationIDAbiological_process
GO:0051260protein homooligomerizationISSbiological_process
GO:0050731positive regulation of peptidyl-tyrosine phosphoryIEAbiological_process
GO:0032869cellular response to insulin stimulusISSbiological_process
GO:0005515protein bindingIEAmolecular_function
GO:0045860positive regulation of protein kinase activityIEAbiological_process
GO:0005783endoplasmic reticulumIEAcellular_component
GO:0005576extracellular regionTAScellular_component
GO:0006006glucose metabolic processIEAbiological_process
GO:0031667response to nutrient levelsIEAbiological_process
GO:2000481positive regulation of cAMP-dependent protein kinaIDAbiological_process
GO:0043123positive regulation of I-kappaB kinase/NF-kappaB cIEAbiological_process
GO:2000534positive regulation of renal albumin absorptionIDAbiological_process
GO:0033691sialic acid bindingIDAmolecular_function
GO:0046326positive regulation of glucose importIEAbiological_process
GO:0071872cellular response to epinephrine stimulusIEAbiological_process
GO:0030853negative regulation of granulocyte differentiationIDAbiological_process
GO:0014823response to activityIEAbiological_process
GO:0005179hormone activityIEAmolecular_function
GO:0070208protein heterotrimerizationIEAbiological_process
GO:0005125cytokine activityNASmolecular_function
GO:0032869cellular response to insulin stimulusIEAbiological_process
GO:0042802identical protein bindingTASmolecular_function
GO:2000467positive regulation of glycogen (starch) synthase ISSbiological_process
GO:0034115negative regulation of heterotypic cell-cell adhesIDAbiological_process
GO:0042593glucose homeostasisIEAbiological_process
GO:0006635fatty acid beta-oxidationISSbiological_process
GO:0009744response to sucrose stimulusIEAbiological_process
GO:0006006glucose metabolic processISSbiological_process
GO:0045892negative regulation of transcription, DNA-dependenIDAbiological_process
GO:0042593glucose homeostasisISSbiological_process
GO:0006635fatty acid beta-oxidationIEAbiological_process
GO:0070543response to linoleic acidIEAbiological_process
GO:0070994detection of oxidative stressISSbiological_process
GO:0050728negative regulation of inflammatory responseIEAbiological_process
GO:0019395fatty acid oxidationIEAbiological_process
GO:0046326positive regulation of glucose importISSbiological_process
GO:0050765negative regulation of phagocytosisIDAbiological_process
GO:0034383low-density lipoprotein particle clearanceIDAbiological_process
GO:0045471response to ethanolIEAbiological_process
GO:0005783endoplasmic reticulumISScellular_component
GO:0045777positive regulation of blood pressureIEAbiological_process
GO:0009749response to glucose stimulusISSbiological_process
GO:2000584negative regulation of platelet-derived growth facISSbiological_process
GO:0005615extracellular spaceIEAcellular_component
GO:0005102receptor bindingISSmolecular_function
GO:0045923positive regulation of fatty acid metabolic procesIEAbiological_process
GO:0050873brown fat cell differentiationISSbiological_process
GO:0050728negative regulation of inflammatory responseISSbiological_process
GO:0045776negative regulation of blood pressureIDAbiological_process
GO:0010804negative regulation of tumor necrosis factor-mediaIDAbiological_process
GO:0033211adiponectin-mediated signaling pathwayIEAbiological_process
GO:0009749response to glucose stimulusIEAbiological_process
GO:2000534positive regulation of renal albumin absorptionIEAbiological_process
GO:0048662negative regulation of smooth muscle cell proliferIDAbiological_process
GO:0005179hormone activityIDAmolecular_function
GO:0031953negative regulation of protein autophosphorylationIDAbiological_process
GO:0043499eukaryotic cell surface bindingIDAmolecular_function
GO:0010642negative regulation of platelet-derived growth facIEAbiological_process
GO:0001666response to hypoxiaIEAbiological_process
GO:0045721negative regulation of gluconeogenesisISSbiological_process
GO:0007584response to nutrientIEAbiological_process
GO:0009967positive regulation of signal transductionIEAbiological_process
GO:0034612response to tumor necrosis factorIDAbiological_process
GO:0009967positive regulation of signal transductionISSbiological_process